Xia Zhe1, Kang Liu2, Yun-Feng Mu2, Shun Qi2, Yi-Bin Xi2, Ping Du2, Yi Huan2, Qing-Rong Tan3, Hong Yin4, Hai-Tao Zhao2, Ya-Li Ge2, Ying-Juan Chang2. 1. Department of Radiology, Xijing Hospital, Fourth Military Medical University, 17 Changle Road, Xi'an, Shaanxi 710032, China; Department of Radiology, Shaanxi People's Hospital, Xi'an, Shaanxi 710032, China. 2. Department of Radiology, Xijing Hospital, Fourth Military Medical University, 17 Changle Road, Xi'an, Shaanxi 710032, China. 3. Department of Psychiatry, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, China. 4. Department of Radiology, Xijing Hospital, Fourth Military Medical University, 17 Changle Road, Xi'an, Shaanxi 710032, China. Electronic address: yinhong@fmmu.edu.cn.
Abstract
RATIONALE AND OBJECTIVES: This study evaluated the altered regional cerebral blood flow (rCBF) in resting state in patients with acute posttraumatic stress disorder (PTSD) 3 months after trauma. MATERIALS AND METHODS: The rCBF was measured in 30 patients with acute PTSD and 36 healthy controls. RESULTS: Survivors with acute PTSD showed decreased rCBF, the Clinician-Administered PTSD Scale score correlated negatively with the rCBF, and rCBF at resting state decreased in acute PTSD. CONCLUSIONS: PTSD symptom severity was associated with diminished cerebral blood flow in the right insular cortex and right orbital medial frontal gyrus. The rCBF may predict PTSD symptom severity.
RATIONALE AND OBJECTIVES: This study evaluated the altered regional cerebral blood flow (rCBF) in resting state in patients with acute posttraumatic stress disorder (PTSD) 3 months after trauma. MATERIALS AND METHODS: The rCBF was measured in 30 patients with acute PTSD and 36 healthy controls. RESULTS: Survivors with acute PTSD showed decreased rCBF, the Clinician-Administered PTSD Scale score correlated negatively with the rCBF, and rCBF at resting state decreased in acute PTSD. CONCLUSIONS:PTSD symptom severity was associated with diminished cerebral blood flow in the right insular cortex and right orbital medial frontal gyrus. The rCBF may predict PTSD symptom severity.
Authors: Dianne A Cruz; Leisa A Glantz; Kara D McGaughey; Gillian Parke; Lawrence J Shampine; Jason D Kilts; Jennifer C Naylor; Christine E Marx; Douglas E Williamson Journal: Chronic Stress (Thousand Oaks) Date: 2019-04-18
Authors: Danielle R Sullivan; David H Salat; Erika J Wolf; Mark W Logue; Catherine B Fortier; Jennifer R Fonda; Joseph DeGutis; Michael Esterman; William P Milberg; Regina E McGlinchey; Mark W Miller Journal: Neuroimage Clin Date: 2020-08-01 Impact factor: 4.891