Literature DB >> 27280621

Comparison of Enzyme Immunoassays for Detection of Antibodies to Hepatitis D Virus in Serum.

Siu-Kei Chow1, Ederlyn E Atienza1, Linda Cook1, Harry Prince2, Patricia Slev3, Mary Lapé-Nixon2, Keith R Jerome4.   

Abstract

Serology remains critical for diagnosing hepatitis D virus (HDV) infection, which affects 15 to 20 million people worldwide, but the literature on characterizing commercial enzyme immunoassays (EIAs) dates back to 15 years ago. We evaluated 2 commercial EIAs currently available for detecting anti-HDV antibodies. The DiaSorin assay demonstrated 100% sensitivity and specificity. Using a modified cutoff value, the Cusabio assay demonstrated a sensitivity of 81.3% and specificity of 90.9%. Our data show that recently developed EIAs are reliable for anti-HDV antibody detection.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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Year:  2016        PMID： 27280621      PMCID： PMC4979180          DOI： 10.1128/CVI.00028-16

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  10 in total

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5.  Development of a hepatitis delta virus antibody assay for study of the prevalence of HDV among individuals infected with hepatitis B virus in China.

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  10 in total
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6.  Anti-HDV seroprevalance among patients with previous HBV infection.

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7.  Transmission of Hepatitis B and D Viruses in an African Rural Community.

Authors:  Carlos Augusto Pinho-Nascimento; Martin W Bratschi; Rene Höfer; Caroline Cordeiro Soares; Louisa Warryn; Jūlija Pečerska; Jacques C Minyem; Izabel C N P Paixão; Marcia Terezinha Baroni de Moraes; Alphonse Um Boock; Christian Niel; Gerd Pluschke; Katharina Röltgen
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  7 in total

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