Literature DB >> 27279240

Review of the GAS3 Family of Proteins and their Relevance to Cancer.

Negin Ashki1, Lynn Gordon2, Madhuri Wadehra3.   

Abstract

The GAS3 family of tetraspan proteins has recently been implicated in the progression of cancer. Currently, six members of the GAS3 family have been identified in humans and mice, and while their expressions in disease vary, data suggest that they play a role in epithelial cell structure and function. In this review, we highlight the studies implicating four of the members in disease pathogenesis as well as probe the structural similarities between the family members. Finally, the impact of targeting select members of the family such as PMP22 and EMP2 is discussed.

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Year:  2015        PMID： 27279240      PMCID： PMC5362274          DOI： 10.1615/CritRevOncog.v20.i5-6.140

Source DB:  PubMed          Journal:  Crit Rev Oncog        ISSN： 0893-9675


  96 in total

1.  A growth arrest-specific (gas) gene codes for a membrane protein.

Authors:  G Manfioletti; M E Ruaro; G Del Sal; L Philipson; C Schneider
Journal:  Mol Cell Biol       Date:  1990-06       Impact factor: 4.272

2.  Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas.

Authors:  Markus Bredel; Claudia Bredel; Dejan Juric; Griffith R Harsh; Hannes Vogel; Lawrence D Recht; Branimir I Sikic
Journal:  Cancer Res       Date:  2005-10-01       Impact factor: 12.701

3.  The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer.

Authors:  Laszlo Radvanyi; Devender Singh-Sandhu; Scott Gallichan; Corey Lovitt; Artur Pedyczak; Gustavo Mallo; Kurt Gish; Kevin Kwok; Wedad Hanna; Judith Zubovits; Jane Armes; Deon Venter; Jalil Hakimi; Jean Shortreed; Melinda Donovan; Mark Parrington; Pamela Dunn; Ray Oomen; James Tartaglia; Neil L Berinstein
Journal:  Proc Natl Acad Sci U S A       Date:  2005-07-25       Impact factor: 11.205

4.  Differences in gene expression in the proliferative human endometrium.

Authors:  Atsushi Yanaihara; Yukiko Otsuka; Shinji Iwasaki; Tadateru Aida; Tetsuhiko Tachikawa; Taro Irie; Takashi Okai
Journal:  Fertil Steril       Date:  2005-04       Impact factor: 7.329

5.  Impairment of peroxisomal biogenesis in human colon carcinoma.

Authors:  C Lauer; A Völkl; S Riedl; H D Fahimi; K Beier
Journal:  Carcinogenesis       Date:  1999-06       Impact factor: 4.944

6.  EMP3 overexpression is associated with oligodendroglial tumors retaining chromosome arms 1p and 19q.

Authors:  Kay Ka Wai Li; Jesse Chung-Sean Pang; Nellie Yuk-Fei Chung; Yeung Lam Ng; Norman Hok Ling Chan; Liangfu Zhou; Wai Sang Poon; Ho-Keung Ng
Journal:  Int J Cancer       Date:  2007-02-15       Impact factor: 7.396

7.  The gene for the peripheral myelin protein PMP-22 is a candidate for Charcot-Marie-Tooth disease type 1A.

Authors:  P I Patel; B B Roa; A A Welcher; R Schoener-Scott; B J Trask; L Pentao; G J Snipes; C A Garcia; U Francke; E M Shooter; J R Lupski; U Suter
Journal:  Nat Genet       Date:  1992-06       Impact factor: 38.330

8.  Charcot-Marie-Tooth disease type 1A. Association with a spontaneous point mutation in the PMP22 gene.

Authors:  B B Roa; C A Garcia; U Suter; D A Kulpa; C A Wise; J Mueller; A A Welcher; G J Snipes; E M Shooter; P I Patel; J R Lupski
Journal:  N Engl J Med       Date:  1993-07-08       Impact factor: 91.245

9.  Identification and characterization of a novel squamous cell-associated gene related to PMP22.

Authors:  K W Marvin; W Fujimoto; A M Jetten
Journal:  J Biol Chem       Date:  1995-12-01       Impact factor: 5.157

Review 10.  Peripheral myelin protein 22: facts and hypotheses.

Authors:  U Suter; G J Snipes
Journal:  J Neurosci Res       Date:  1995-02-01       Impact factor: 4.164
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  3 in total

Review 1.  Unraveling the structures, functions and mechanisms of epithelial membrane protein family in human cancers.

Authors:  Nan Zhang; Hong-Ping Zhu; Wei Huang; Xiang Wen; Xin Xie; Xian Jiang; Cheng Peng; Bo Han; Gu He
Journal:  Exp Hematol Oncol       Date:  2022-10-10

2.  Elevated Peripheral Myelin Protein 22, Reduced Mitotic Potential, and Proteasome Impairment in Dermal Fibroblasts from Charcot-Marie-Tooth Disease Type 1A Patients.

Authors:  Sooyeon Lee; Hannah Bazick; Vinita Chittoor-Vinod; Mohammed Omar Al Salihi; Guangbin Xia; Lucia Notterpek
Journal:  Am J Pathol       Date:  2017-12-12       Impact factor: 4.307

3.  Genetic Deletion of Emp2 Does Not Cause Proteinuric Kidney Disease in Mice.

Authors:  Michael D Donnan; Rizaldy P Scott; Tuncer Onay; Antoine Tarjus; Ummiye Venus Onay; Susan E Quaggin
Journal:  Front Med (Lausanne)       Date:  2019-08-27
  3 in total

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