Literature DB >> 27274165

Uremic Toxins - Novel Arrhythmogenic Factor in Chronic Kidney Disease - Related Atrial Fibrillation.

Shih-Yu Huang1, Yi-Ann Chen2, Shih-Ann Chen3, Yi-Jen Chen4, Yung-Kuo Lin5.   

Abstract

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Chronic kidney disease (CKD) is associated with a high prevalence of AF, and uremic toxins are an important risk factor for cardiovascular diseases associated with CKD. Uremic toxins can produce pro-fibrotic, pro-hypertrophic, and pro-inflammatory effects on cardiac tissues and enhance oxidative stress or neurohormonal phenomena of cardiovascular injury, which are recognized as arrhythmogenic factors of AF. This article reviews the clinical, molecular, and electrophysiological data of uremic toxins in CKD considered to induce AF through multiple mechanisms on structural and electrical remodeling of the cardiovascular system.

Entities:  

Keywords:  Atrial fibrillation; Inflammation; Oxidative stress; Uremic toxins

Year:  2016        PMID: 27274165      PMCID: PMC4884752          DOI: 10.6515/acs20151116a

Source DB:  PubMed          Journal:  Acta Cardiol Sin        ISSN: 1011-6842            Impact factor:   2.672


  48 in total

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Journal:  Clin Exp Pharmacol Physiol       Date:  2011-10       Impact factor: 2.557

4.  Uremic toxin p-cresol induces disassembly of gap junctions of cardiomyocytes.

Authors:  Yu-Sen Peng; Hsiu-Chi Ding; Yen-Tung Lin; Jhih-Pu Syu; Ying Chen; Seu-Mei Wang
Journal:  Toxicology       Date:  2012-07-17       Impact factor: 4.221

5.  p-Cresol and cardiovascular risk in mild-to-moderate kidney disease.

Authors:  Björn K I Meijers; Kathleen Claes; Bert Bammens; Henriette de Loor; Liesbeth Viaene; Kristin Verbeke; Dirk Kuypers; Yves Vanrenterghem; Pieter Evenepoel
Journal:  Clin J Am Soc Nephrol       Date:  2010-04-29       Impact factor: 8.237

6.  Oxidative stress on pulmonary vein and left atrium arrhythmogenesis.

Authors:  Yung-Kuo Lin; Feng-Zhi Lin; Yao-Chang Chen; Chen-Chuan Cheng; Cheng-I Lin; Yi-Jen Chen; Shih-Ann Chen
Journal:  Circ J       Date:  2010-06-16       Impact factor: 2.993

7.  Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients.

Authors:  Fellype C Barreto; Daniela V Barreto; Sophie Liabeuf; Natalie Meert; Griet Glorieux; Mohammed Temmar; Gabriel Choukroun; Raymond Vanholder; Ziad A Massy
Journal:  Clin J Am Soc Nephrol       Date:  2009-08-20       Impact factor: 8.237

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Journal:  Kidney Int       Date:  2008-02-27       Impact factor: 10.612

9.  Endothelin-1 modulates the arrhythmogenic activity of pulmonary veins.

Authors:  Ameya R Udyavar; Yao-Chang Chen; Yi-Jen Chen; Chen-Chuan Cheng; Cheng-I Lin; Shih-Ann Chen
Journal:  J Cardiovasc Electrophysiol       Date:  2008-03

10.  Chronic kidney disease-induced cardiac fibrosis is ameliorated by reducing circulating levels of a non-dialysable uremic toxin, indoxyl sulfate.

Authors:  Suree Lekawanvijit; Andrew R Kompa; Minako Manabe; Bing H Wang; Robyn G Langham; Fuyuhiko Nishijima; Darren J Kelly; Henry Krum
Journal:  PLoS One       Date:  2012-07-19       Impact factor: 3.240

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  5 in total

Review 1.  Cardiorenal syndrome: long road between kidney and heart.

Authors:  Carolina Victoria Cruz Junho; Mayra Trentin-Sonoda; Karine Panico; Raquel Silva Neres Dos Santos; Mariana Vieira Abrahão; Imara Caridad Stable Vernier; Cristina Ribas Fürstenau; Marcela Sorelli Carneiro-Ramos
Journal:  Heart Fail Rev       Date:  2022-02-08       Impact factor: 4.654

Review 2.  Short-Chain Fatty Acids in Chronic Kidney Disease: Focus on Inflammation and Oxidative Stress Regulation.

Authors:  Giorgia Magliocca; Pasquale Mone; Biagio Raffaele Di Iorio; August Heidland; Stefania Marzocco
Journal:  Int J Mol Sci       Date:  2022-05-11       Impact factor: 6.208

3.  A Reliable Method: Purse-String Hemostasis for Arteriovenous Fistula or Arteriovenous Graft Cannulation after Percutaneous Transluminal Angioplasty.

Authors:  Sheng-Hong Shi; Tien-Jen Chen
Journal:  Acta Cardiol Sin       Date:  2018-11       Impact factor: 2.672

4.  Indoxyl Sulphate is Associated with Atrial Fibrillation Recurrence after Catheter Ablation.

Authors:  Fumi Yamagami; Kazuko Tajiri; Kosuke Doki; Masayuki Hattori; Junya Honda; Satoshi Aita; Tomohiko Harunari; Hiro Yamasaki; Nobuyuki Murakoshi; Yukio Sekiguchi; Masato Homma; Naohiko Takahashi; Kazutaka Aonuma; Akihiko Nogami; Masaki Ieda
Journal:  Sci Rep       Date:  2018-11-22       Impact factor: 4.379

Review 5.  Inflammation and Oxidative Stress in Chronic Kidney Disease-Potential Therapeutic Role of Minerals, Vitamins and Plant-Derived Metabolites.

Authors:  Shara Francesca Rapa; Biagio Raffaele Di Iorio; Pietro Campiglia; August Heidland; Stefania Marzocco
Journal:  Int J Mol Sci       Date:  2019-12-30       Impact factor: 5.923

  5 in total

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