Literature DB >> 27273937

Epigenetic mechanisms in endometrial cancer.

Albiona Stampoliou1, Petroula Arapantoni-Dadioti, Kitty Pavlakis.   

Abstract

Purpose: Endometrial cancer is a very common type of cancer in females worldwide. Advances in diagnosis and treatment have not decreased the incidence of endometrial cancer. Lately, research has been focused on revealing the molecular and genetic characteristics of endometrial cancer in order to provide new insights in the biology of this entity, leading hopefully to innovating therapies. Research has revealed that epigenetic modifications govern endometrial carcinogenesis. In this review, the epigenetic mechanisms that are involved in endometrial cancer as well as the differences between the different types of endometrial cancer are discussed. The review also refers to the putative therapeutic benefits that hopefully can arise.

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Year:  2016        PMID： 27273937

Source DB:  PubMed          Journal:  J BUON        ISSN： 1107-0625            Impact factor:   2.533


  9 in total

1.  [Methyltransferase inhibitor BIX01294 promotes the migration and inhibits decidualization of mouse uterine stromal cells in vitro].

Authors:  Hui-Qi Liao; Liu Tian; Hui Yang; Ni Ma; Chang-Jun Zhang; Hong-Lu Diao
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2017-06-20

2.  Prognostic value of an autophagy-related gene expression signature for endometrial cancer patients.

Authors:  Hui Wang; Xiaoling Ma; Jinhui Liu; Yicong Wan; Yi Jiang; Yankai Xia; Wenjun Cheng
Journal:  Cancer Cell Int       Date:  2020-07-13       Impact factor: 5.722

3.  Frequent promoter methylation of HOXD10 in endometrial carcinoma and its pathological significance.

Authors:  Fan Yang; Dongchen Liu; Yupeng Deng; Jun Wang; Shuyu Mei; Shuang Ge; Hailing Li; Cuijuan Zhang; Tingguo Zhang
Journal:  Oncol Lett       Date:  2020-03-19       Impact factor: 2.967

Review 4.  Targeting Epigenetic Regulators for Endometrial Cancer Therapy: Its Molecular Biology and Potential Clinical Applications.

Authors:  Futaba Inoue; Kenbun Sone; Yusuke Toyohara; Yu Takahashi; Asako Kukita; Aki Hara; Ayumi Taguchi; Michihiro Tanikawa; Tetsushi Tsuruga; Yutaka Osuga
Journal:  Int J Mol Sci       Date:  2021-02-25       Impact factor: 5.923

5.  Identification of a MicroRNA Signature Associated With Lymph Node Metastasis in Endometrial Endometrioid Cancer.

Authors:  Kaiyou Fu; Yanrui Li; Jianyuan Song; Wangyu Cai; Wei Wu; Xiaohang Ye; Jian Xu
Journal:  Front Genet       Date:  2021-04-15       Impact factor: 4.599

6.  Loss of ten-eleven translocation 1 (TET1) expression as a diagnostic and prognostic biomarker of endometrial carcinoma.

Authors:  Nien-Tzu Liu; Cherng-Lih Perng; Yu-Ching Chou; Pi-Shao Ko; Yi-Jia Lin; Yu-Chun Lin; Cheng-Chang Chang; Yu-Chi Wang; Hung-Sheng Shang; Tai-Kuang Chao
Journal:  PLoS One       Date:  2021-11-03       Impact factor: 3.240

7.  Methylation status of KLF4 and HS3ST2 genes as predictors of endometrial cancer and hyperplastic endometrial lesions.

Authors:  Zuzana Danková; Dušan Braný; Dana Dvorská; Marcela Ňachajová; Roman Fiolka; Marián Grendár; Jozef Hatok; Peter Kubatka; Veronika Holubeková; Erika Halašová; Tibor Bielik; Pavol Žúbor
Journal:  Int J Mol Med       Date:  2018-09-12       Impact factor: 4.101

8.  Prospects of NSAIDs administration as double-edged agents against endometrial cancer and pathological species of the uterine microbiome.

Authors:  Olga Kuźmycz; Paweł Stączek
Journal:  Cancer Biol Ther       Date:  2020-03-15       Impact factor: 4.742

9.  Comprehensive Analysis of Copy Number Variation, Nucleotide Mutation, and Transcription Level of PPAR Pathway-Related Genes in Endometrial Cancer.

Authors:  Minghui Tang; Jingyao Wang; Liangsheng Fan
Journal:  PPAR Res       Date:  2022-01-13       Impact factor: 4.964
  9 in total

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