Literature DB >> 27273808

Versatility of pedicled anterolateral thigh flap in gynecologic reconstruction after vulvar cancer extirpative surgery.

Stefano Gentileschi1, Maria Servillo1, Giorgia Garganese2, Fragomeni Simona2, Giovanni Scambia2, Marzia Salgarello1.   

Abstract

OBJECTIVE: Ablative surgery for vulvar cancer can involve the resection of perineum, vagina, urethra, groins, mons pubis, and abdominal wall creating complex defects. In our opinion, ALT flap is an ideal flap for reconstruction, because of low incidence of complications, long pedicle outside the radiotherapy field, capability of carrying fascia and muscle, possibility of sensate reconstruction, and low donor site morbidity. The purpose of this report is to describe our experience with ALT flap for reconstruction after vulvar cancer extirpative surgery, discussing our indications for complex defects and focusing on its versatility. PATIENTS AND METHODS: We performed a retrospective review of 15 cases of complex postoncologic gynecological wounds, reconstructed with 16 pedicled ALT flap, after vulvar cancer ablative surgery between 2014 and 2016. Age of the patients ranged from 44 to 77, with mean age of 62.6. Postoperative outcomes were evaluated.
RESULTS: The flap size ranged from 12 × 8 cm to 22 × 15 cm., in two cases we harvested vastus lateralis to fill the dead space after pelvic exenteration. In nine flaps, we could include only 1 perforator, in 7 we could use two, 5 were septocutaneous and 18 myocutaneous with a pedicle length ranging from9cm.to15cm.We had no flap necrosis.3 flaps showed dehiscence of a part of the wound that healed by dressings. In one case of obese patient the donor site showed partial wound edge necrosis, and required secondary grafting. During follow-up that ranged from 1 month to 2 years, cancer relapsed locally in 5 patients. Global performance and specific pain improved after surgery.
CONCLUSION: ALT flap should be included in the first line options for reconstructions of complex defects resulting from vulvar cancer surgery because of its reliability and versatility.
© 2016 Wiley Periodicals, Inc. Microsurgery 37:516-524, 2017. © 2016 Wiley Periodicals, Inc.

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Year:  2016        PMID: 27273808     DOI: 10.1002/micr.30077

Source DB:  PubMed          Journal:  Microsurgery        ISSN: 0738-1085            Impact factor:   2.425


  8 in total

1.  Lymphatic Function of the Lower Limb after Groin Dissection for Vulvar Cancer and Reconstruction with Lymphatic SCIP Flap.

Authors:  Anna Amelia Caretto; Gianluigi Stefanizzi; Simona Maria Fragomeni; Alex Federico; Luca Tagliaferri; Valentina Lancellotta; Giovanni Scambia; Stefano Gentileschi
Journal:  Cancers (Basel)       Date:  2022-02-21       Impact factor: 6.639

2.  Surgical therapy of vulvar cancer: how to choose the correct reconstruction?

Authors:  Stefano Gentileschi; Maria Servillo; Giorgia Garganese; Simona Fragomeni; Francesca De Bonis; Giovanni Scambia; Marzia Salgarello
Journal:  J Gynecol Oncol       Date:  2016-07-12       Impact factor: 4.401

3.  Safety and feasibility of single-incision radical vulvectomy: a novel approach for the treatment of vulvar cancer.

Authors:  Liqing He; Gaowen Chen; Xiaoxuan Li; Youhong Zheng; Mengting Wu; Huiyan Wang; Xiaohong Liu; Wuqi He; Xiaodan Liu; Shaozhuo Huang; Fan Lin; Weixin Liao; Ying Ma; Yifeng Wang
Journal:  Ann Transl Med       Date:  2021-02

4.  Reconstructive Surgery versus Primary Closure following Vulvar Cancer Excision: A Wide Single-Center Experience.

Authors:  Mustafa Zelal Muallem; Jalid Sehouli; Andrea Miranda; Helmut Plett; Ahmad Sayasneh; Yasser Diab; Jumana Muallem; Imad Hatoum
Journal:  Cancers (Basel)       Date:  2022-03-26       Impact factor: 6.639

5.  Personalizing vulvar cancer workflow in COVID-19 era: a proposal from Vul.Can MDT.

Authors:  Giorgia Garganese; Luca Tagliaferri; Simona Maria Fragomeni; Valentina Lancellotta; Giuseppe Colloca; Giacomo Corrado; Stefano Gentileschi; Gabriella Macchia; Enrica Tamburrini; Maria Antonietta Gambacorta; Anna Fagotti; Giovanni Scambia
Journal:  J Cancer Res Clin Oncol       Date:  2020-07-12       Impact factor: 4.553

6.  Versatility of the pedicled anterolateral thigh flap for surgical reconstruction, a case series.

Authors:  Christoffer Bing Madsen; Jens Ahm Sørensen
Journal:  JPRAS Open       Date:  2020-06-13

Review 7.  Building a Personalized Medicine Infrastructure for Gynecological Oncology Patients in a High-Volume Hospital.

Authors:  Nicolò Bizzarri; Camilla Nero; Francesca Sillano; Francesca Ciccarone; Marika D'Oria; Alfredo Cesario; Simona Maria Fragomeni; Antonia Carla Testa; Francesco Fanfani; Gabriella Ferrandina; Domenica Lorusso; Anna Fagotti; Giovanni Scambia
Journal:  J Pers Med       Date:  2021-12-21

8.  The Vulvar Immunohistochemical Panel (VIP) Project: Molecular Profiles of Vulvar Squamous Cell Carcinoma.

Authors:  Giorgia Garganese; Frediano Inzani; Simona Maria Fragomeni; Giulia Mantovani; Luigi Della Corte; Alessia Piermattei; Angela Santoro; Giuseppe Angelico; Luciano Giacò; Giacomo Corrado; Anna Fagotti; Gian Franco Zannoni; Giovanni Scambia
Journal:  Cancers (Basel)       Date:  2021-12-19       Impact factor: 6.639

  8 in total

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