| Literature DB >> 27272586 |
Roy G Elbers1, Henk W Berendse2, Gert Kwakkel3.
Abstract
CLINICAL QUESTION: Which pharmacological and nonpharmacological interventions are associated with improvement in general, physical, or mental fatigue and minimal adverse effects in patients with Parkinson disease (PD)? BOTTOM LINE: Rasagiline, modafinil, and doxepin are associated with improvement in fatigue and are not associated with increased risk of adverse effects in patients with PD. However, the quality of evidence is limited and does not provide a clear basis for treatment decisions.Entities:
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Year: 2016 PMID: 27272586 DOI: 10.1001/jama.2016.5260
Source DB: PubMed Journal: JAMA ISSN: 0098-7484 Impact factor: 56.272