Literature DB >> 27272390

Enantioselective Palladium-Catalyzed Oxidative β,β-Fluoroarylation of α,β-Unsaturated Carbonyl Derivatives.

Javier Miró1, Carlos Del Pozo2, F Dean Toste3, Santos Fustero4,5.   

Abstract

The site-selective palladium-catalyzed three-component coupling of deactivated alkenes, arylboronic acids, and N-fluorobenzenesulfonimide is disclosed herein. The developed methodology establishes a general, modular, and step-economical approach to the stereoselective β-fluorination of α,β-unsaturated systems.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  alkenes; fluorine; palladium; reaction mechanisms; synthetic methods

Mesh：

Substances：

Year:  2016        PMID： 27272390      PMCID： PMC6482284          DOI： 10.1002/anie.201603046

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  9 in total

1.  Further Developments and Applications of Oxazoline-Containing Ligands in Asymmetric Catalysis.

Authors:  Robert Connon; Brendan Roche; Balaji V Rokade; Patrick J Guiry
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2.  Mechanistic Investigations of the Pd(0)-Catalyzed Enantioselective 1,1-Diarylation of Benzyl Acrylates.

Authors:  Manuel Orlandi; Margaret J Hilton; Eiji Yamamoto; F Dean Toste; Matthew S Sigman
Journal:  J Am Chem Soc       Date:  2017-08-30       Impact factor: 15.419

3.  Assessment of Cooperativity in Ternary Peptide-Cucurbit[8]uril Complexes.

Authors:  Emanuela Cavatorta; Pascal Jonkheijm; Jurriaan Huskens
Journal:  Chemistry       Date:  2017-03-14       Impact factor: 5.236

4.  The development and mechanistic investigation of a palladium-catalyzed 1,3-arylfluorination of chromenes.

Authors:  Richard T Thornbury; Vaneet Saini; Talita de A Fernandes; Celine B Santiago; Eric P A Talbot; Matthew S Sigman; Jeffrey M McKenna; F Dean Toste
Journal:  Chem Sci       Date:  2017-02-09       Impact factor: 9.825

5.  Catalytic Synthesis of 5-Fluoro-2-oxazolines: Using BF3·Et2O as the Fluorine Source and Activating Reagent.

Authors:  Hongli Chai; Xiang Zhen; Xueqing Wang; Liang Qi; Yuji Qin; Jijun Xue; Zhaoqing Xu; Hongrui Zhang; Weiwei Zhu
Journal:  ACS Omega       Date:  2022-06-01

Review 6.  Walking metals: catalytic difunctionalization of alkenes at nonclassical sites.

Authors:  Roshan K Dhungana; Rishi R Sapkota; Doleshwar Niroula; Ramesh Giri
Journal:  Chem Sci       Date:  2020-09-07       Impact factor: 9.825

7.  A Transient Directing Group Strategy Enables Enantioselective Multicomponent Organofluorine Synthesis.

Authors:  Zhonglin Liu; Lucas J Oxtoby; Mingyu Liu; Zi-Qi Li; Van T Tran; Yang Gao; Keary M Engle
Journal:  J Am Chem Soc       Date:  2021-06-02       Impact factor: 16.383

8.  A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3.

Authors:  Pim J de Vink; Jeroen M Briels; Thomas Schrader; Lech-Gustav Milroy; Luc Brunsveld; Christian Ottmann
Journal:  Angew Chem Int Ed Engl       Date:  2017-06-29       Impact factor: 15.336

9.  Cucurbit[8]uril Reactivation of an Inactivated Caspase-8 Mutant Reveals Differentiated Enzymatic Substrate Processing.

Authors:  Dung T Dang; Arthur H A M van Onzen; Yvonne L Dorland; Luc Brunsveld
Journal:  Chembiochem       Date:  2018-11-05       Impact factor: 3.164
  9 in total

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