Literature DB >> 27269768

Symptoms, functioning and coping strategies in individuals with schizophrenia spectrum disorders who do not take antipsychotic medication: a comparative interview study.

E Jung1, M Wiesjahn1, H Wendt2, T Bock3, W Rief1, T M Lincoln2.   

Abstract

BACKGROUND: A considerable proportion of people with schizophrenia spectrum disorders do not take antipsychotic medication but seem to be functioning well. However, little is known about this group. To test the assumption that absence of medication is compensated for by more effective coping and increased social support, this study compared symptoms, functioning, coping strategies and social support in non-medicated and medicated individuals with schizophrenia spectrum disorders.
METHOD: In all, 48 participants with a DSM-IV schizophrenia spectrum disorder who were taking (n = 25) or not taking antipsychotic medication (n = 23) were included. Assessment consisted of self-ratings of symptoms, symptom-related distress and social support combined with a semi-structured interview that assessed general and social functioning, subjective evaluation of symptoms and coping strategies.
RESULTS: Symptom severity and distress did not differ between the groups. However, the non-medicated participants had significantly higher levels of general functioning than medicated participants and a longer duration of being non-medicated was significantly associated with a higher level of general functioning. In contrast to the hypotheses, not taking medication was not associated with more effective coping strategies or with higher levels of social support. Medicated participants more frequently reported the use of professional help as a coping strategy.
CONCLUSIONS: Our results corroborate previous studies finding improved functioning in individuals with schizophrenia spectrum disorders who do not take medication compared with those who take medication, but do not support the notion that this difference is explicable by better coping or higher levels of social support. Alternative explanations and avenues for research are discussed.

Entities:  

Keywords:  Antipsychotic medication; coping; functioning; non-medicated patients; schizophrenia

Mesh:

Substances:

Year:  2016        PMID: 27269768     DOI: 10.1017/S0033291716000775

Source DB:  PubMed          Journal:  Psychol Med        ISSN: 0033-2917            Impact factor:   7.723


  6 in total

1.  Attempting to stop antipsychotic medication: success, supports, and efforts to cope.

Authors:  Miriam Larsen-Barr; Fred Seymour; John Read; Kerry Gibson
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2018-04-23       Impact factor: 4.328

2.  A 20-Year multi-followup longitudinal study assessing whether antipsychotic medications contribute to work functioning in schizophrenia.

Authors:  Martin Harrow; Thomas H Jobe; Robert N Faull; Jie Yang
Journal:  Psychiatry Res       Date:  2017-06-22       Impact factor: 3.222

3.  Using Open Questions to Understand 650 People's Experiences With Antipsychotic Drugs.

Authors:  John Read; Ann Sacia
Journal:  Schizophr Bull       Date:  2020-07-08       Impact factor: 9.306

4.  Experiences of antipsychotic use in patients with early psychosis: a two-year follow-up study.

Authors:  Rafal A H Yeisen; Jone Bjornestad; Inge Joa; Jan Olav Johannessen; Stein Opjordsmoen
Journal:  BMC Psychiatry       Date:  2017-08-22       Impact factor: 3.630

5.  Positive and Negative Effects of Antipsychotic Medication: An International Online Survey of 832 Recipients.

Authors:  John Read; James Williams
Journal:  Curr Drug Saf       Date:  2019

6.  Service-user efforts to maintain their wellbeing during and after successful withdrawal from antipsychotic medication.

Authors:  Miriam Larsen-Barr; Fred Seymour
Journal:  Ther Adv Psychopharmacol       Date:  2021-01-31
  6 in total

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