Bayard R Wilson1, Jeffrey A Steinberg2, Vivian Snyder3, Michael N Jiang1, Bob S Carter4. 1. School of Medicine, University of California at San Diego, San Diego, California, USA. 2. Department of Neurosurgery, University of California at San Diego, San Diego, California, USA. Electronic address: J1steinberg@ucsd.edu. 3. Department of Pathology, Division of Neuropathology, University of California at San Diego, San Diego, California, USA. 4. Department of Neurosurgery, University of California at San Diego, San Diego, California, USA.
Abstract
BACKGROUND: The phenomenon of intracerebral schwannoma is exceedingly rare, and its etiology still a matter of debate. No documented cases of intracerebral schwannoma containing vascular elements consistent with those of an arteriovenous malformation (AVM) have been reported. We describe such a case here. CASE DESCRIPTION: A left temporal intraparenchymal lesion was discovered incidentally in a 34-year-old man after he suffered a mild trauma. The lesion was resected and found on histologic examination to be an intracerebral schwannoma with AVM-like vasculature. The patient made a full recovery after resection. CONCLUSIONS: To our knowledge, this is the first case of an intracerebral schwannoma with AVM-like characteristics to be reported in the literature. We hypothesize that the co-occurrence of this rare pathologic entity is caused by an interrelated etiologic process, with the tumor microenvironment of the schwannoma inciting the development of the vascular malformation.
BACKGROUND: The phenomenon of intracerebral schwannoma is exceedingly rare, and its etiology still a matter of debate. No documented cases of intracerebral schwannoma containing vascular elements consistent with those of an arteriovenous malformation (AVM) have been reported. We describe such a case here. CASE DESCRIPTION: A left temporal intraparenchymal lesion was discovered incidentally in a 34-year-old man after he suffered a mild trauma. The lesion was resected and found on histologic examination to be an intracerebral schwannoma with AVM-like vasculature. The patient made a full recovery after resection. CONCLUSIONS: To our knowledge, this is the first case of an intracerebral schwannoma with AVM-like characteristics to be reported in the literature. We hypothesize that the co-occurrence of this rare pathologic entity is caused by an interrelated etiologic process, with the tumor microenvironment of the schwannoma inciting the development of the vascular malformation.
Authors: William W Scott; Korgun Koral; Linda R Margraf; Laura Klesse; David J Sacco; Bradley E Weprin Journal: J Neurosurg Pediatr Date: 2013-05-10 Impact factor: 2.375