Literature DB >> 27267605

SGK-1 and PHLPP1: Ras-mediated effectors during ECM-detachment.

Joshua A Mason1, Zachary T Schafer1.   

Abstract

Entities:  

Keywords:  ECM-detachment; PHLPP1; Ras; SGK-1; anoikis; metabolism; metastasis

Mesh：

Substances：

Year:  2016        PMID： 27267605      PMCID： PMC5004674          DOI： 10.1080/15384101.2016.1194136

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer.

Authors:  Maxwell N Skor; Erin L Wonder; Masha Kocherginsky; Anju Goyal; Ben A Hall; Yi Cai; Suzanne D Conzen
Journal:  Clin Cancer Res       Date:  2013-09-09       Impact factor: 12.531

2.  Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells.

Authors:  J A Mason; C A Davison-Versagli; A K Leliaert; D J Pape; C McCallister; J Zuo; S M Durbin; C L Buchheit; S Zhang; Z T Schafer
Journal:  Cell Death Differ       Date:  2016-02-26       Impact factor: 15.828

3.  The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachment.

Authors:  Raju R Rayavarapu; Brendan Heiden; Nicholas Pagani; Melissa M Shaw; Sydney Shuff; Siyuan Zhang; Zachary T Schafer
Journal:  J Biol Chem       Date:  2015-02-13       Impact factor: 5.157

4.  PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.

Authors:  Tianyan Gao; Frank Furnari; Alexandra C Newton
Journal:  Mol Cell       Date:  2005-04-01       Impact factor: 17.970

Review 5.  Cancer cell survival during detachment from the ECM: multiple barriers to tumour progression.

Authors:  Cassandra L Buchheit; Kelsey J Weigel; Zachary T Schafer
Journal:  Nat Rev Cancer       Date:  2014-08-07       Impact factor: 60.716

6.  CAF-secreted IGFBPs regulate breast cancer cell anoikis.

Authors:  Kelsey J Weigel; Ana Jakimenko; Brooke A Conti; Sarah E Chapman; William J Kaliney; W Matthew Leevy; Matthew M Champion; Zachary T Schafer
Journal:  Mol Cancer Res       Date:  2014-05-06       Impact factor: 5.852

7.  Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment.

Authors:  Zachary T Schafer; Alexandra R Grassian; Loling Song; Zhenyang Jiang; Zachary Gerhart-Hines; Hanna Y Irie; Sizhen Gao; Pere Puigserver; Joan S Brugge
Journal:  Nature       Date:  2009-08-19       Impact factor: 49.962
  7 in total
  2 in total

Review 1.  Role of Forkhead Box Class O proteins in cancer progression and metastasis.

Authors:  Chang Geun Kim; Hyemin Lee; Nehal Gupta; Sharavan Ramachandran; Itishree Kaushik; Sangeeta Srivastava; Sung-Hoon Kim; Sanjay K Srivastava
Journal:  Semin Cancer Biol       Date:  2017-08-01       Impact factor: 15.707

2.  Ras-ling with new therapeutic targets for metastasis.

Authors:  Joshua A Mason; Zachary T Schafer
Journal:  Small GTPases       Date:  2017-05-04
  2 in total

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