| Literature DB >> 27267542 |
M Bhanuchandra1, Alexandre Baralle1, Shinya Otsuka1, Keisuke Nogi1, Hideki Yorimitsu1, Atsuhiro Osuka1.
Abstract
A catalytic Miyaura-type ipso-borylation of aryl sulfides with diboron reagents has been achieved, providing arylboronate esters of synthetic use. The key conditions to transform inherently reluctant C-S bonds into C-B bonds include a palladium-NHC (N-heterocyclic carbene) precatalyst, bis(pinacolato)diboron, and lithium hexamethyldisilazide. This protocol is applicable to a reasonable range of aryl alkyl sulfides. Twofold borylation was observed in the reaction of diphenyl sulfide.Entities:
Year: 2016 PMID： 27267542 DOI： 10.1021/acs.orglett.6b01305
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005