Literature DB >> 27266651

Case reports of aconite poisoning in mainland China from 2004 to 2015: A retrospective analysis.

Haoran Li1, Liang Liu2, Shaohua Zhu3, Qian Liu4.   

Abstract

Aconitum species have long been used in key traditional medicines in China, but cases of fatal aconite poisoning have also been reported. This paper presents a review of 40 single and multi-person cases of fatal aconite poisoning. The cases involved 53 victims in mainland China described in 27 case reports published between January 2004 and September 2015. We summarize the details of the case reports in order to highlight the features of fatal aconite-poisoning cases in China, including victims' sex and age, route of intoxication, clinical symptoms, medicolegal autopsy findings, and results of toxicological analysis. Our results indicate a need for legal medical experts encountering cases of fatal aconite poisoning to pay increased attention to the methods used for collecting biological samples. In addition, prevention strategies should focus on increasing public awareness regarding the potential toxicity of Aconitum, harm caused by medicinal liquors containing aconitine, and possibility of Aconitum alkaloids accumulating in the body.
Copyright © 2016 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Entities:  

Keywords:  Aconitine; Aconitum; Autopsy; Fatal poisoning; Retrospective study

Mesh:

Substances:

Year:  2016        PMID: 27266651     DOI: 10.1016/j.jflm.2016.05.016

Source DB:  PubMed          Journal:  J Forensic Leg Med        ISSN: 1752-928X            Impact factor:   1.614


  10 in total

1.  An Updated Meta-Analysis Based on the Preclinical Evidence of Mechanism of Aconitine-Induced Cardiotoxicity.

Authors:  Hong Jiang; Yating Zhang; Yi Zhang; Xiaobo Wang; Xianli Meng
Journal:  Front Pharmacol       Date:  2022-06-08       Impact factor: 5.988

Review 2.  Research progress of aconitine toxicity and forensic analysis of aconitine poisoning.

Authors:  Xiangting Gao; Jun Hu; Xincai Zhang; Yuanyi Zuo; Yun Wang; Shaohua Zhu
Journal:  Forensic Sci Res       Date:  2018-04-09

3.  Potential Molecular Mechanisms and Drugs for Aconitine-Induced Cardiotoxicity in Zebrafish through RNA Sequencing and Bioinformatics Analysis.

Authors:  Mingzhu Wang; Yanan Shi; Lei Yao; Qiang Li; Youhua Wang; Deyu Fu
Journal:  Med Sci Monit       Date:  2020-06-29

Review 4.  Relationships between the Toxicities of Radix Aconiti Lateralis Preparata (Fuzi) and the Toxicokinetics of Its Main Diester-Diterpenoid Alkaloids.

Authors:  Mengbi Yang; Xiaoyu Ji; Zhong Zuo
Journal:  Toxins (Basel)       Date:  2018-09-26       Impact factor: 4.546

5.  An Intentional Aconite Overdose: A Case Report.

Authors:  Christopher Wood; James Coulson; John Thompson; Stephen Bonner
Journal:  J Crit Care Med (Targu Mures)       Date:  2020-05-06

6.  Forensic appraisal of death due to acute alcohol poisoning: three case reports and a literature review.

Authors:  Hui Wang; Hongmei Xu; Wencan Li; Beixu Li; Qun Shi; Kaijun Ma; Bi Xiao; Long Chen
Journal:  Forensic Sci Res       Date:  2019-03-18

7.  Revealing the efficacy-toxicity relationship of Fuzi in treating rheumatoid arthritis by systems pharmacology.

Authors:  Wuwen Feng; Juan Liu; Dandan Zhang; Yuzhu Tan; Hao Cheng; Cheng Peng
Journal:  Sci Rep       Date:  2021-11-29       Impact factor: 4.379

8.  Poisoning Associated with Consumption of a Homemade Medicinal Liquor - Chongqing, China, 2018.

Authors:  Chunbei Zhou; Shuquan Luo; Jiang Tang; Linda Quick; Huihui Liu; Yinan Zhao
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2022-04-22       Impact factor: 17.586

Review 9.  The toxicology and detoxification of Aconitum: traditional and modern views.

Authors:  Yau-Tuen Chan; Ning Wang; Yibin Feng
Journal:  Chin Med       Date:  2021-07-27       Impact factor: 5.455

10.  A system for reporting and evaluating adverse drug reactions of herbal medicine in Taiwan from 1998 to 2016.

Authors:  Hen-Hong Chang; Su-Yin Chiang; Pei-Chun Chen; Chia-Han Tsai; Rong-Chi Yang; Chiu-Lin Tsai; Tsung-Hsiu Wu; Yow-Wen Hsieh; Yu-Chun Lin; Yung-Te Kuo; Kuan-Chung Chen; Hsueh-Ting Chu
Journal:  Sci Rep       Date:  2021-11-02       Impact factor: 4.379

  10 in total

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