Splenomegaly due to the use of granulocyte-colony stimulating factor.

Granulocyte-colony stimulating factor (G-CSF) is a growth factor used for stem-cell mobilization and neutropenia treatment. We report that splenomegaly was detected in a 16-years-old patient with acute lymphoblastic leukemia following the administration of G-CSF. The presence of splenomegaly in the patients receiving G-CSF may be related to the use of G-CSF.