Sjoerd Nell1, Laurent Brunaud2, Ahmet Ayav2, Bert A Bonsing3, Bas Groot Koerkamp4, Els J Nieveen van Dijkum5, Geert Kazemier6, Ruben H J de Kleine7, Jeroen Hagendoorn8, I Quintus Molenaar8, Gerlof D Valk9, Inne H M Borel Rinkes10, Menno R Vriens11. 1. Department of Endocrine Surgical Oncology and Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands. 2. Department of Digestive, Hepatobiliary and Endocrine Surgery, Université de Lorraine, Hôpital Brabois Adultes, CHU Nancy, Nancy, France. 3. Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands. 4. Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands. 5. Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands. 6. Department of Surgery, VU University Medical Center, Amsterdam, The Netherlands. 7. Department of Hepatobiliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. 8. Department of Surgical Oncology and Hepato-Pancreato-Biliary Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. 9. Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands. 10. Department of Surgical Oncology and Endocrine Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands. 11. Department of Endocrine Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
Abstract
BACKGROUND: Multiple Endocrine Neoplasia type 1 (MEN1) patients often undergo multiple pancreatic operations at a young age. OBJECTIVE: To describe robot-assisted and laparoscopic spleen-preserving pancreatic surgery in MEN1 patients, and to compare both techniques. METHODS: Robot-assisted pancreatectomies of the DutchMEN1 study group and the Université de Lorraine, Nancy, France were compared to a historical cohort of laparoscopic treated MEN1 patients. Perioperative outcomes were compared. RESULTS: A total of 21 MEN1 patients underwent minimally invasive pancreatic surgery for pancreatic neuroendocrine tumors, seven patients were subjected to robot-assisted surgery, and 14 patients underwent laparoscopic surgery. Demographics and clinical characteristics did not differ between the cohorts and no significant differences in operative outcomes were found. A high number of ISGPS grade B/C pancreatic fistulas were observed in both cohorts (38%), and no conversions were seen in the robot-assisted cohort (respectively 0% vs. 43%, P = 0.06). In one laparoscopic and one robot-assisted case the primary tumor was not resected. CONCLUSIONS: Minimally invasive spleen-preserving surgery in MEN1 patients is safe and feasible. Patients who underwent robot-assisted surgery did not require conversion to open surgery. J. Surg. Oncol. 2016;114:456-461.
BACKGROUND:Multiple Endocrine Neoplasia type 1 (MEN1) patients often undergo multiple pancreatic operations at a young age. OBJECTIVE: To describe robot-assisted and laparoscopic spleen-preserving pancreatic surgery in MEN1patients, and to compare both techniques. METHODS: Robot-assisted pancreatectomies of the DutchMEN1 study group and the Université de Lorraine, Nancy, France were compared to a historical cohort of laparoscopic treated MEN1patients. Perioperative outcomes were compared. RESULTS: A total of 21 MEN1patients underwent minimally invasive pancreatic surgery for pancreatic neuroendocrine tumors, seven patients were subjected to robot-assisted surgery, and 14 patients underwent laparoscopic surgery. Demographics and clinical characteristics did not differ between the cohorts and no significant differences in operative outcomes were found. A high number of ISGPS grade B/C pancreatic fistulas were observed in both cohorts (38%), and no conversions were seen in the robot-assisted cohort (respectively 0% vs. 43%, P = 0.06). In one laparoscopic and one robot-assisted case the primary tumor was not resected. CONCLUSIONS: Minimally invasive spleen-preserving surgery in MEN1patients is safe and feasible. Patients who underwent robot-assisted surgery did not require conversion to open surgery. J. Surg. Oncol. 2016;114:456-461.
Authors: Dirk-Jan van Beek; Rachel S van Leeuwaarde; Carolina Rc Pieterman; Menno R Vriens; Gerlof D Valk Journal: Endocr Connect Date: 2018-09-01 Impact factor: 3.335