Literature DB >> 27263362

From Mendel to epigenetics: History of genetics.

Jean Gayon1.   

Abstract

The origins of genetics are to be found in Gregor Mendel's memoir on plant hybridization (1865). However, the word 'genetics' was only coined in 1906, to designate the new science of heredity. Founded upon the Mendelian method for analyzing the products of crosses, this science is distinguished by its explicit purpose of being a general 'science of heredity', and by the introduction of totally new biological concepts (in particular those of gene, genotype, and phenotype). In the 1910s, Mendelian genetics fused with the chromosomal theory of inheritance, giving rise to what is still called 'classical genetics'. Within this framework, the gene is simultaneously a unit of function and transmission, a unit of recombination, and of mutation. Until the early 1950s, these concepts of the gene coincided. But when DNA was found to be the material basis of inheritance, this congruence dissolved. Then began the venture of molecular biology, which has never stopped revealing the complexity of the way in which hereditary material functions.
Copyright © 2016 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Keywords:  Biologie moléculaire; Chromosomal theory of inheritance; Gene; Gène; Génétique mendélienne; Mendel; Mendelian genetics; Molecular biology; Théorie chromosomique de l’hérédité

Mesh:

Year:  2016        PMID: 27263362     DOI: 10.1016/j.crvi.2016.05.009

Source DB:  PubMed          Journal:  C R Biol        ISSN: 1631-0691            Impact factor:   1.583


  12 in total

1.  From phenotype to genotype: celebrating 150 years of Mendelian genetics in plant breeding research.

Authors:  Johann Vollmann; Hermann Buerstmayr
Journal:  Theor Appl Genet       Date:  2016-11-14       Impact factor: 5.699

2.  Primer in Genetics and Genomics, Article 6: Basics of Epigenetic Control.

Authors:  Kristen L Fessele; Fay Wright
Journal:  Biol Res Nurs       Date:  2017-11-23       Impact factor: 2.522

3.  Fruit quality and DNA methylation are affected by parental order in reciprocal crosses of tomato.

Authors:  Magalí Diana Gimenez; Dana Valeria Vazquez; Felipe Trepat; Vladimir Cambiaso; Gustavo Rubén Rodríguez
Journal:  Plant Cell Rep       Date:  2020-10-20       Impact factor: 4.570

Review 4.  Epigenetics and microRNAs in UGT1As.

Authors:  Cui-Lan Meng; Wei Zhao; Dan-Ni Zhong
Journal:  Hum Genomics       Date:  2021-05-25       Impact factor: 4.639

Review 5.  Genetic control of non-genetic inheritance in mammals: state-of-the-art and perspectives.

Authors:  A Tomar; R Teperino
Journal:  Mamm Genome       Date:  2020-06-11       Impact factor: 2.957

Review 6.  Genomic Analysis, Progress and Future Perspectives in Dairy Cattle Selection: A Review.

Authors:  Miguel A Gutierrez-Reinoso; Pedro M Aponte; Manuel Garcia-Herreros
Journal:  Animals (Basel)       Date:  2021-02-25       Impact factor: 3.231

Review 7.  Epi-miRNAs: Regulators of the Histone Modification Machinery in Human Cancer.

Authors:  Deniz Mortazavi; Behnoush Sohrabi; Meysam Mosallaei; Ziba Nariman-Saleh-Fam; Milad Bastami; Yaser Mansoori; Abdolreza Daraei; Sepideh Zununi Vahed; Shadan Navid; Zahra Saadatian; Tannaz Jamialahmadi; Yong Teng; Amirhossein Sahebkar
Journal:  J Oncol       Date:  2022-01-11       Impact factor: 4.375

Review 8.  DNA Methylation and Schizophrenia: Current Literature and Future Perspective.

Authors:  Thabo Magwai; Khanyiso Bright Shangase; Fredrick Otieno Oginga; Bonginkosi Chiliza; Thabisile Mpofana; Khethelo Richman Xulu
Journal:  Cells       Date:  2021-10-26       Impact factor: 6.600

Review 9.  Epigenetic Regulation of Hepatocellular Carcinoma Progression through the mTOR Signaling Pathway.

Authors:  Mengnan Guo; Ning Li; Jianxia Zheng; Wei Wang; Yan Wu; Xu Han; Jiapei Guo; Weixi Chen; Zekun Bai; Wen Bai; Jinghua Wu
Journal:  Can J Gastroenterol Hepatol       Date:  2021-05-25

10.  Adolescent Substance Abuse, Transgenerational Consequences and Epigenetics.

Authors:  Hamed Salmanzadeh; S Mohammad Ahmadi-Soleimani; Maryam Azadi; Robert F Halliwell; Hossein Azizi
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.363

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