Takuma Tsukioka1, Makoto Takahama2, Ryu Nakajima2, Michitaka Kimura2, Hidetoshi Inoue2, Ryoji Yamamoto2. 1. Department of General Thoracic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima Hondori, Miyakojima-ku, Osaka, 534-0021, Japan. t-tsukioka@med.osaka-cu.ac.jp. 2. Department of General Thoracic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima Hondori, Miyakojima-ku, Osaka, 534-0021, Japan.
Abstract
BACKGROUND: Pulmonary and left atrial resection is not yet an established treatment for patients with primary lung cancer involving the left atrium. We investigated the clinical course of patients with primary lung cancer involving the left atrium who were treated with pulmonary resection and partial atrial resection. METHODS: From January 1996 to December 2013, 51 patients underwent extended resection for lung cancer that invaded the surrounding organs. Of these, we focused on 12 patients who underwent surgical treatment for lung cancer involving the left atrium. The clinical course of each of these patients was investigated retrospectively. RESULTS: The most common histological subtype was squamous cell carcinoma. Pneumonectomy was performed in nine patients, and right middle and lower lobectomy was performed in three patients. Complete resection was performed in 11 patients (92 %). Postoperative complications were observed in four patients (33 %)-prolonged air leakage in two patients, broncho-pleural fistula in one patient, and empyema in one patient. There were no surgical deaths. This study involved seven patients with pathological N0-1 disease and five patients with pathological N2 disease. The postoperative 5-year survival rate was 46 % in all patients. The 5-year survival rates in patients with pathological N0-1 disease and N2 disease were 67 and 20 %, respectively. CONCLUSION: Because treatment-related death was not observed and outcome was fair in patients with N0-1 disease, surgical resection for primary lung cancer involving the left atrium may be acceptable in selected patients. Further investigations are required to improve the outcome of surgical treatment for patients with primary lung cancer involving the left atrium.
BACKGROUND: Pulmonary and left atrial resection is not yet an established treatment for patients with primary lung cancer involving the left atrium. We investigated the clinical course of patients with primary lung cancer involving the left atrium who were treated with pulmonary resection and partial atrial resection. METHODS: From January 1996 to December 2013, 51 patients underwent extended resection for lung cancer that invaded the surrounding organs. Of these, we focused on 12 patients who underwent surgical treatment for lung cancer involving the left atrium. The clinical course of each of these patients was investigated retrospectively. RESULTS: The most common histological subtype was squamous cell carcinoma. Pneumonectomy was performed in nine patients, and right middle and lower lobectomy was performed in three patients. Complete resection was performed in 11 patients (92 %). Postoperative complications were observed in four patients (33 %)-prolonged air leakage in two patients, broncho-pleural fistula in one patient, and empyema in one patient. There were no surgical deaths. This study involved seven patients with pathological N0-1 disease and five patients with pathological N2 disease. The postoperative 5-year survival rate was 46 % in all patients. The 5-year survival rates in patients with pathological N0-1 disease and N2 disease were 67 and 20 %, respectively. CONCLUSION: Because treatment-related death was not observed and outcome was fair in patients with N0-1 disease, surgical resection for primary lung cancer involving the left atrium may be acceptable in selected patients. Further investigations are required to improve the outcome of surgical treatment for patients with primary lung cancer involving the left atrium.
Entities:
Keywords:
Left atrium; Primary lung cancer; Surgical treatment
Authors: Ashok Muralidaran; Frank C Detterbeck; Daniel J Boffa; Zuoheng Wang; Anthony W Kim Journal: J Thorac Cardiovasc Surg Date: 2011-08-23 Impact factor: 5.209
Authors: R S Akchurin; M I Davidov; S A Partigulov; J B Brand; A A Shiriaev; M G Lepilin; I M Dolgov Journal: Artif Organs Date: 1997-07 Impact factor: 3.094
Authors: Andreas Kuehnl; Michael Lindner; Hans-Martin Hornung; Hauke Winter; Karl-Walter Jauch; Rudolf A Hatz; Christian Graeb Journal: World J Surg Date: 2010-09 Impact factor: 3.352
Authors: Geraud Galvaing; Marie M Tardy; Lucie Cassagnes; Valinkini Da Costa; Jean Baptiste Chadeyras; Adel Naamee; Patrick Bailly; Edith Filaire; Bruno Pereira; Marc Filaire Journal: Ann Thorac Surg Date: 2014-03-10 Impact factor: 4.330
Authors: Lorenzo Spaggiari; Massimiliano D' Aiuto; Giulia Veronesi; Giuseppe Pelosi; Tommaso de Pas; Gianpiero Catalano; Filippo de Braud Journal: Ann Thorac Surg Date: 2005-01 Impact factor: 4.330
Authors: Giovanni B Ratto; Roberta Costa; Giuseppe Vassallo; Antonella Alloisio; Paola Maineri; Paolo Bruzzi Journal: Ann Thorac Surg Date: 2004-07 Impact factor: 4.330
Authors: Shadi Hamouri; Nasr Alrabadi; Sebawe Syaj; Hassan Abushukair; Obada Ababneh; Leen Al-Kraimeen; Majd Al-Sous; Erich Hecker Journal: Surg Today Date: 2022-01-09 Impact factor: 2.549