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Literature DB >> 27262925

PLA micro- and nano-particles.

Byung Kook Lee¹, Yeonhee Yun¹, Kinam Park².

Abstract

Poly(d,l-lactic acid) (PLA) has been widely used for various biomedical applications for its biodegradable, biocompatible, and nontoxic properties. Various methods, such as emulsion, salting out, and precipitation, have been used to make better PLA micro- and nano-particle formulations. They are widely used as controlled drug delivery systems of therapeutic molecules, including proteins, genes, vaccines, and anticancer drugs. Even though PLA-based particles have challenges to overcome, such as low drug loading capacity, low encapsulation efficiency, and terminal sterilization, continuous innovations in particulate formulations will lead to development of clinically useful formulations.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: Drug delivery system; Fabrication methods; Micro-particles; Nano-particles; PLA

Mesh：

Substances：

Year: 2016 PMID： 27262925 PMCID： PMC5133193 DOI： 10.1016/j.addr.2016.05.020

Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470

127 in total

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Journal: Pharm Res Date: 2000-10 Impact factor: 4.200

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Authors: Hajime Katou; Anne Julia Wandrey; Bruno Gander
Journal: Int J Pharm Date: 2008-08-22 Impact factor: 5.875

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Authors: W Jiang; S P Schwendeman
Journal: Pharm Res Date: 2001-06 Impact factor: 4.200

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Authors: Indu Barwal; Anil Sood; Mohit Sharma; Bikram Singh; Subhash C Yadav
Journal: Colloids Surf B Biointerfaces Date: 2012-07-17 Impact factor: 5.268

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Authors: M F Zambaux; F Bonneaux; R Gref; E Dellacherie; C Vigneron
Journal: J Control Release Date: 1999-08-05 Impact factor: 9.776

6. Novel powder formulations for controlled delivery of poorly soluble anticancer drug: application and investigation of TPGS and PEG in spray-dried particulate system.

Authors: Li Mu; More-Ming Teo; Hui-Zhong Ning; Chou-Song Tan; Si-Shen Feng
Journal: J Control Release Date: 2005-04-18 Impact factor: 9.776

7. Delivery of vanillin by poly(lactic-acid) nanoparticles: Development, characterization and in vitro evaluation of antioxidant activity.

Authors: Luciana Facco Dalmolin; Najeh Maissar Khalil; Rubiana Mara Mainardes
Journal: Mater Sci Eng C Mater Biol Appl Date: 2016-01-16 Impact factor: 7.328

8. Preparation, characterization, cytotoxicity and transfection efficiency of poly(DL-lactide-co-glycolide) and poly(DL-lactic acid) cationic nanoparticles for controlled delivery of plasmid DNA.

Authors: Ashwin Basarkar; Dilip Devineni; Ravi Palaniappan; Jagdish Singh
Journal: Int J Pharm Date: 2007-05-18 Impact factor: 5.875

9. Formulation of HIV-1 Tat and p24 antigens by PLA nanoparticles or MF59 impacts the breadth, but not the magnitude, of serum and faecal antibody responses in rabbits.

Authors: Christophe Guillon; Katia Mayol; Céline Terrat; Christelle Compagnon; Charlotte Primard; Marie-Hélène Charles; Thierry Delair; Séverine Munier; Bernard Verrier
Journal: Vaccine Date: 2007-09-17 Impact factor: 3.641

10. Chitosan/PLA nanoparticles as a novel carrier for the delivery of anthraquinone: synthesis, characterization and in vitro cytotoxicity evaluation.

Authors: D Jeevitha; Kanchana Amarnath
Journal: Colloids Surf B Biointerfaces Date: 2012-06-28 Impact factor: 5.268

43 in total

1. Physiologically Relevant Mechanics of Biodegradable Polyester Nanoparticles.

Authors: Nourin Alsharif; Behnaz Eshaghi; Björn M Reinhard; Keith A Brown
Journal: Nano Lett Date: 2020-10-05 Impact factor: 11.189

2. Preparation of particulate polymeric therapeutics for medical applications.

Authors: Jia Zhuang; Ronnie H Fang; Liangfang Zhang
Journal: Small Methods Date: 2017-07-25

Review 3. Membrane-core nanoparticles for cancer nanomedicine.

Authors: Jianfeng Guo; Leaf Huang
Journal: Adv Drug Deliv Rev Date: 2020-05-22 Impact factor: 15.470

Review 4. Development of nanomaterials for bone-targeted drug delivery.

Authors: Hao Cheng; Aditya Chawla; Yafeng Yang; Yuxiao Li; Jin Zhang; Hae Lin Jang; Ali Khademhosseini
Journal: Drug Discov Today Date: 2017-05-06 Impact factor: 7.851

5. Fabrication of biodegradable particles with tunable morphologies by the addition of resveratrol to oil in water emulsions.

Authors: Christopher Isely; Alexandra C Stevens; Gregory L Tate; John R Monnier; R Michael Gower
Journal: Int J Pharm Date: 2020-10-03 Impact factor: 5.875

6. Depot Subcutaneous Injection with Chalcone CH8-Loaded Poly(Lactic-Co-Glycolic Acid) Microspheres as a Single-Dose Treatment of Cutaneous Leishmaniasis.

Authors: Ariane de Jesus Sousa-Batista; Wallace Pacienza-Lima; Natalia Arruda-Costa; Camila Alves Bandeira Falcão; Maria Ines Ré; Bartira Rossi-Bergmann
Journal: Antimicrob Agents Chemother Date: 2018-02-23 Impact factor: 5.191

10. The Preparation of a Novel Poly(Lactic Acid)-Based Sustained H₂S Releasing Microsphere for Rheumatoid Arthritis Alleviation.

Authors: Yue Yu; Zhou Wang; Qian Ding; Xiangbin Yu; Qinyan Yang; Ran Wang; Yudong Fang; Wei Qi; Junyi Liao; Wei Hu; Yizhun Zhu
Journal: Pharmaceutics Date: 2021-05-18 Impact factor: 6.321