Literature DB >> 27262755

Is a surgical approach justified for octogenarians with pancreatic carcinoma? Projecting surgical decision making for octogenarian patients.

Takehiro Okabayashi1, Yasuo Shima2, Jun Iwata3, Sojiro Morita4, Tatsuaki Sumiyoshi2, Akihito Kozuki2, Tatsuo Iiyama5, Akihito Nishioka4, Manabu Matsumoto3.   

Abstract

BACKGROUND: In recent years, more elderly patients have undergone surgery for pancreatic cancer, although the safety and efficacy of performing complex pancreatic resections in patients older than 80 years remain controversial.
METHODS: Patients with pancreatic cancer who underwent curative surgical treatment were divided into 2 subgroups: the younger group (<80 years) and the octogenarian group (≥80 years).
RESULTS: From March 2005 to December 2013, 194 consecutive surgically curable patients with diagnosed pancreatic cancer were studied, among which 34 (17.5%) were of 80 years or older. There were no significant differences in postoperative severe complication rates for younger and octogenarian groups (16% vs 20%, respectively) or perioperative mortality rates (1.3% vs .0%). The incidence of postoperative delirium in the octogenarian group was greater than that in the younger group (23.5% vs 3.8%).
CONCLUSIONS: Octogenarian pancreatic cancer patients should not be denied a priori the opportunity for surgery, particularly if the patient represents an ideal candidate and if the co-operation of the family can be obtained.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Carcinoma; Octogenarian; Outcome; Pancreas; Surgery

Mesh:

Year:  2016        PMID: 27262755     DOI: 10.1016/j.amjsurg.2015.12.033

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  5 in total

1.  Correlation between the skeletal muscle index and surgical outcomes of pancreaticoduodenectomy.

Authors:  Kenta Sui; Takehiro Okabayshi; Jun Iwata; Sojiro Morita; Tatsuaki Sumiyoshi; Tatsuo Iiyama; Yasuhiro Shimada
Journal:  Surg Today       Date:  2017-12-28       Impact factor: 2.549

2.  Training surgeons in shared decision-making with cancer patients aged 65 years and older: a pilot study.

Authors:  Noralie H Geessink; Yvonne Schoon; Marcel Gm Olde Rikkert; Harry van Goor
Journal:  Cancer Manag Res       Date:  2017-11-10       Impact factor: 3.989

3.  Indications for pancreaticoduodenectomy affected postoperative outcomes in octogenarians.

Authors:  Takehiro Okabayashi; Kenta Sui; Takahiro Murokawa; Jiro Kimura; Jun Iwata; Sojiro Morita; Tatsuo Iiyama; Yasuhiro Shimada
Journal:  Ann Gastroenterol Surg       Date:  2020-08-31

4.  Comparing Postoperative Complications and Inflammatory Markers Using Total Intravenous Anesthesia Versus Volatile Gas Anesthesia for Pancreatic Cancer Surgery.

Authors:  Jose M Soliz; Ifeyinwa C Ifeanyi; Mathew H Katz; Jonathan Wilks; Juan P Cata; Thomas McHugh; Jason B Fleming; Lei Feng; Thomas Rahlfs; Morgan Bruno; Vijaya Gottumukkala
Journal:  Anesth Pain Med       Date:  2017-08-21

5.  Surgery for elderly patients with resectable pancreatic cancer, a comparison with non-surgical treatments: a retrospective study outcomes of resectable pancreatic cancer.

Authors:  Hyeong Min Park; Sang-Jae Park; Sung-Sik Han; Seoung Hoon Kim
Journal:  BMC Cancer       Date:  2019-11-12       Impact factor: 4.430

  5 in total

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