| Literature DB >> 27262598 |
Mikhail V Chudinov1, Alexander N Prutkov2, Andrey V Matveev2, Lyubov E Grebenkina2, Irina D Konstantinova3, Yulia V Berezovskaya4.
Abstract
A new pathway to synthesis of arylvinyl ribavirin analogues is developed which makes it possible to obtain not only trans- but also cis-isomers at vinyl bond. By this route eight ribavirin 5-arylvinyl analogues are synthesized and their antiviral activity is evaluated.Entities:
Keywords: HCV; Nucleoside analogues; Triazole nucleosides
Mesh：
Substances：
Year: 2016 PMID： 27262598 DOI： 10.1016/j.bmcl.2016.05.072
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823