Literature DB >> 27262489

The variability of corneal and anterior segment parameters in keratoconus.

Enric Mas-Aixala1, Joan Gispets2, Núria Lupón1, Genís Cardona1.   

Abstract

PURPOSE: To analyse, describe and test diverse corneal and anterior segment parameters in normal and keratoconic eyes to better understand the geometry of the keratoconic cornea.
METHOD: 44 eyes from 44 keratoconic patients and 44 eyes from 44 healthy patients were included in the study. The Pentacam System was used for the analysis of the anterior segment parameters. New ad-hoc parameters were defined by measuring the distances on the Scheimpflug image at the horizontal diameter, with chamber depth now comprising of two distinctive distances: corneal sagittal depth and the distance from the endpoint of this segment to the anterior surface of the lens (DL).
RESULTS: Statistically significant differences (p<0.05) between normal and keratoconic eyes were found in all of the analysed corneal parameters. Anterior chamber depth presented statistical differences between normal and keratoconic eyes (3.06±0.43mm versus 3.34±0.45mm, respectively; p=0.004). This difference was found to originate in an increase of the DL distance (0.40±0.33mm in normal eyes against 0.61±0.45mm in keratoconic eyes; p=0.014), rather than in the changes in corneal sagittal depth.
CONCLUSION: These findings indicate that keratoconus results in central and peripheral corneal manifestations, as well as changes in the shape of the scleral limbus. The DL parameter was useful in describing the forward elongation and advance of the scleral tissue in keratoconic eyes. This finding may help in the monitoring of disease progression and contact lens design and fitting.
Copyright © 2016 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Anterior chamber depth; Corneal sagittal depth; Corneal shape; Keratoconus; Scheimpflug imaging; Scleral shape

Mesh:

Year:  2016        PMID: 27262489     DOI: 10.1016/j.clae.2016.05.003

Source DB:  PubMed          Journal:  Cont Lens Anterior Eye        ISSN: 1367-0484            Impact factor:   3.077


  3 in total

1.  Ocular dimensions of the Chinese adolescents with keratoconus.

Authors:  Weijun Jian; Yang Shen; Yingjun Chen; Mi Tian; Xingtao Zhou
Journal:  BMC Ophthalmol       Date:  2018-02-13       Impact factor: 2.209

2.  Evaluation of corneal symmetry after UV corneal crosslinking for keratoconus.

Authors:  Hanan Mofty; Khaled Alzahrani; Fiona Carley; Sophie Harper; Arun Brahma; Leon Au; Debbie Morley; M Chantal Hillarby
Journal:  Clin Ophthalmol       Date:  2017-11-20

3.  Comparison of Anterior Chamber Depth between Normal and Keratoconic Eyes: A Systematic Review and Meta-Analysis.

Authors:  Hassan Hashemi; AbbasAli Yekta; Negareh Yazdani; Hadi Ostadimoghaddam; Mehdi Khabazkhoob
Journal:  J Curr Ophthalmol       Date:  2020-03-23
  3 in total

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