Michelle C Rogerson1, Michael R Le Grande2, David W Dunstan3, Dianna J Magliano4, Barbara M Murphy5, Jo Salmon6, Paul A Gardiner7, Alun C Jackson8. 1. Australian Centre for Heart Health, Melbourne, Vic., Australia. Electronic address: michelle.rogerson@heartresearchcentre.org. 2. Australian Centre for Heart Health, Melbourne, Vic., Australia; Deakin University, Faculty of Health, Melbourne, Vic., Australia. 3. Baker IDI Heart and Diabetes Institute, Melbourne, Vic., Australia; Australian Catholic University, Mary MacKillop Institute for Health Research, Melbourne, Vic., Australia; The University of Queensland, School of Public Health, Brisbane, Qld., Australia; Deakin University, School of Exercise and Nutrition Sciences, Melbourne, Vic., Australia; The University of Western Australia, School of Sport Science, Exercise and Health, Perth, WA, Australia; Monash University, Department of Medicine, Monash University, Melbourne, Vic., Australia; Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Vic., Australia. 4. Baker IDI Heart and Diabetes Institute, Melbourne, Vic., Australia. 5. Australian Centre for Heart Health, Melbourne, Vic., Australia; Deakin University, Faculty of Health, Melbourne, Vic., Australia; University of Melbourne, Department of Psychology, Melbourne, Vic., Australia; University of Newcastle School of Medicine & Public Health, Newcastle, NSW, Australia. 6. Deakin University, Centre for Physical Activity and Nutrition Research, Melbourne, Vic., Australia. 7. The University of Queensland, School of Public Health, Brisbane, Qld., Australia; The University of Queensland, Mater Research Institute, Brisbane, Qld., Australia. 8. Australian Centre for Heart Health, Melbourne, Vic., Australia; Deakin University, Office of the Pro Vice Chancellor (Health), Melbourne, Vic., Australia; University of Hong Kong, Centre on Behavioural Health, Hong Kong.
Abstract
BACKGROUND: In the general population, excessive sedentary behaviour is associated with increased all-cause mortality. Few studies have examined this relationship in people with cardiovascular disease (CVD). Using a sample of people with CVD who were excluded from an analysis of the Australian Diabetes, Obesity and Lifestyle (AusDiab) study, we examined the relationship between sedentary behaviour and 13-year all-cause mortality. METHODS: In the original AusDiab study, television viewing time was used as a marker of sedentary behaviour in 609 adults (≥45 years of age) with CVD. During 6,291 person-years of follow-up (median follow-up 13 years), there were 294 deaths (48% of sample). Using the time scale of attained age, the Cox proportional hazards model predicting all-cause mortality adjusted for sex, self-rated general health, leisure-time physical activity, smoking status, education, household income, body mass index, lipid levels, blood pressure, and diabetes mellitus was used. RESULTS: Compared with a TV viewing time of <2hours per day, the fully adjusted hazard ratios for all-cause mortality were 1.18 (95% CI, 0.88 to 1.57) for ≥2 to <4hours per day and 1.52 (95% CI, 1.09 to 2.13) for >4hours per day. CONCLUSIONS: Sedentary behaviour was associated with increased risk of all-cause mortality in people with CVD, independent of physical activity and other confounders. In addition to the promotion of regular physical activity, cardiac rehabilitation efforts which also focus on reducing sedentary behaviour may be beneficial.
BACKGROUND: In the general population, excessive sedentary behaviour is associated with increased all-cause mortality. Few studies have examined this relationship in people with cardiovascular disease (CVD). Using a sample of people with CVD who were excluded from an analysis of the Australian Diabetes, Obesity and Lifestyle (AusDiab) study, we examined the relationship between sedentary behaviour and 13-year all-cause mortality. METHODS: In the original AusDiab study, television viewing time was used as a marker of sedentary behaviour in 609 adults (≥45 years of age) with CVD. During 6,291 person-years of follow-up (median follow-up 13 years), there were 294 deaths (48% of sample). Using the time scale of attained age, the Cox proportional hazards model predicting all-cause mortality adjusted for sex, self-rated general health, leisure-time physical activity, smoking status, education, household income, body mass index, lipid levels, blood pressure, and diabetes mellitus was used. RESULTS: Compared with a TV viewing time of <2hours per day, the fully adjusted hazard ratios for all-cause mortality were 1.18 (95% CI, 0.88 to 1.57) for ≥2 to <4hours per day and 1.52 (95% CI, 1.09 to 2.13) for >4hours per day. CONCLUSIONS: Sedentary behaviour was associated with increased risk of all-cause mortality in people with CVD, independent of physical activity and other confounders. In addition to the promotion of regular physical activity, cardiac rehabilitation efforts which also focus on reducing sedentary behaviour may be beneficial.
Authors: Miranda M Broadney; Britni R Belcher; David A Berrigan; Robert J Brychta; Ira L Tigner; Faizah Shareef; Alexia Papachristopoulou; Jacob D Hattenbach; Elisabeth K Davis; Sheila M Brady; Shanna B Bernstein; Amber B Courville; Bart E Drinkard; Kevin P Smith; Douglas R Rosing; Pamela L Wolters; Kong Y Chen; Jack A Yanovski Journal: Diabetes Care Date: 2018-08-06 Impact factor: 19.112