Literature DB >> 27260623

[Vitreous metastasis of malignant cutaneous melanoma during treatment with ipilimumab].

N Kellermann1, M Maier2, N Feucht2.   

Abstract

An isolated metastasis of the vitreous body from a malignant cutaneous melanoma without involvement of the choroid is an extremely rare occurrence. We report on the case of a 59-year-old female patient who presented with a vitreous body metastasis during systemic treatment with the anti-cytotoxic T lymphocyte-associated antigen (anti-CTLA 4) antibody ipilimumab. This case report underlines the diagnostic difficulties in such cases and points out the risk of metastasis in immune-privileged sites under systemic immunotherapy.

Entities:  

Keywords:  Ipilimumab; Malignant melanoma; Vitrectomy; Vitreous body; Vitreous metastasis

Mesh：

Substances：

Year:  2017        PMID： 27260623     DOI： 10.1007/s00347-016-0271-3

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN： 0941-293X            Impact factor:   1.059


  6 in total

1.  Ocular diseases in metastatic cutaneous melanoma: review of 108 consecutive patients in two German tertiary centers.

Authors:  Rafael S Grajewski; Beatrice Schuler-Thurner; Cornelia Mauch; Nicole Kreuzberg; Konrad R Koch; Antonio Bergua; Claus Cursiefen; Ludwig M Heindl
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-01-22       Impact factor: 3.117

Review 2.  Cutaneous melanoma metastatic to the vitreous cavity.

Authors:  K Gündüz; J A Shields; C L Shields; R C Eagle
Journal:  Ophthalmology       Date:  1998-04       Impact factor: 12.079

Review 3.  Cutaneous malignant melanoma metastatic to the eye, lids, and orbit.

Authors:  Caroline Rosenberg; Paul T Finger
Journal:  Surv Ophthalmol       Date:  2008 May-Jun       Impact factor: 6.048

4.  A case of cutaneous melanoma metastatic to the vitreous cavity: possible pathomechanism and review of the literature.

Authors:  Gesine B Jaissle; Peter Szurman; Jens Martin Rohrbach; Faik Gelisken; Karl Ulrich Bartz-Schmidt
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-11-22       Impact factor: 3.535

Review 5.  Novel Approaches to Treatment of Advanced Melanoma: A Review on Targeted Therapy and Immunotherapy.

Authors:  Anna Niezgoda; Piotr Niezgoda; Rafał Czajkowski
Journal:  Biomed Res Int       Date:  2015-06-10       Impact factor: 3.411

6.  Retinal vasculitis and ocular vitreous metastasis following complete response to PD-1 inhibition in a patient with metastatic cutaneous melanoma.

Authors:  Joshua S Manusow; Leila Khoja; Nataly Pesin; Anthony M Joshua; Efrem D Mandelcorn
Journal:  J Immunother Cancer       Date:  2014-12-16       Impact factor: 13.751
  6 in total
  1 in total

Review 1.  Metastatic tumours to the eye. Review of metastasis to the iris, ciliary body, choroid, retina, optic disc, vitreous, and/or lens capsule.

Authors:  Carol L Shields; Nicholas E Kalafatis; Maikel Gad; Mrittika Sen; Andrea Laiton; Ana Maria Velasco Silva; Kushal Agrawal; Sara E Lally; Jerry A Shields
Journal:  Eye (Lond)       Date:  2022-03-19       Impact factor: 3.775
  1 in total

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