Literature DB >> 27260603

Post-intubation acute laryngeal injuries in infants and children: A new classification system.

Cláudia Schweiger1, Denise Manica2, Gabriel Kuhl3, Leo Sekine4, Paulo José Cauduro Marostica5.   

Abstract

OBJECTIVE: To compare the Classification of Acute Laryngeal Injuries (CALI) with other classifications to determine which of these offers the greatest sensitivity and specificity in predicting the development of subglottic stenosis.
METHODS: All children intubated for the first time in the pediatric intensive care unit were included and subjected to flexible fiber-optic laryngoscopy (FFL) within 8 h of extubation. Their injuries were categorized using the CALI, as well as adapted classifications from Lindholm, Colice and Benjamin. The children were followed up to determine who developed subglottic stenosis.
RESULTS: This study included 194 children, with a median age of 2.67 months. The sensitivity and specificity of the CALI were 90% and 73%, respectively. The CALI showed greater specificity than the adapted classifications from Colice and Benjamin (p < 0.001 for both), and greater sensitivity than the adapted classification from Lindholm (p < 0.001).
CONCLUSIONS: Based on the CALI, 90% of children who developed subglottic stenosis had moderate to severe injuries on the initial FFL. The CALI includes all injury types described by Benjamin, as well as a proposed severity scale for these lesions, and was predictive of the development of chronic laryngeal injury.
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Granulation tissue; Infants; Larynx; Subglottic stenosis; Ulceration

Mesh:

Year:  2016        PMID: 27260603     DOI: 10.1016/j.ijporl.2016.04.032

Source DB:  PubMed          Journal:  Int J Pediatr Otorhinolaryngol        ISSN: 0165-5876            Impact factor:   1.675


  3 in total

1.  Association of endotracheal tube repositioning and acute laryngeal lesions during mechanical ventilation in children.

Authors:  Denise Manica; Catia de Souza Saleh Netto; Cláudia Schweiger; Leo Sekine; Larissa Valency Enéas; Denise Rotta Pereira; Gabriel Kuhl; Paulo Roberto Antonacci Carvalho; Paulo José Cauduro Marostica
Journal:  Eur Arch Otorhinolaryngol       Date:  2017-04-24       Impact factor: 2.503

2.  Ongoing Laryngeal Stenosis: Conservative Management and Alternatives to Tracheostomy.

Authors:  Cláudia Schweiger; Denise Manica
Journal:  Front Pediatr       Date:  2020-04-15       Impact factor: 3.418

3.  Intubation Related Laryngeal Injuries in Pediatric Population.

Authors:  Karma Lambercy; Laurence Pincet; Kishore Sandu
Journal:  Front Pediatr       Date:  2021-02-10       Impact factor: 3.418

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.