BACKGROUND: Group A Streptococcus (GAS) is the most important bacterial cause of acute tonsillitis in children. Some children are chronic GAS carriers, and this carriage is poorly understood. We determined the frequency of GAS detection using a rapid antigen detection test in pediatric patients with indications for tonsillectomy due to adenotonsillar hypertrophy or recurrent GAS infections. METHODS: Seventy-two patients underwent a tonsil swab for a rapid antigen detection test. RESULTS: The GAS rapid antigen detection test was positive in 18.1% of children. GAS was not associated with sex, age or previous history of recurrent tonsillitis. Also, the prevalence of GAS was similar between patients with either recurrent tonsillitis or tonsil hypertrophy. CONCLUSION: In our study, the GAS carriage rate was similar to other reports, and GAS carrier state was not correlated with recurrent tonsillitis.
BACKGROUND:Group A Streptococcus (GAS) is the most important bacterial cause of acute tonsillitis in children. Some children are chronic GAS carriers, and this carriage is poorly understood. We determined the frequency of GAS detection using a rapid antigen detection test in pediatric patients with indications for tonsillectomy due to adenotonsillar hypertrophy or recurrent GAS infections. METHODS: Seventy-two patients underwent a tonsil swab for a rapid antigen detection test. RESULTS: The GAS rapid antigen detection test was positive in 18.1% of children. GAS was not associated with sex, age or previous history of recurrent tonsillitis. Also, the prevalence of GAS was similar between patients with either recurrent tonsillitis or tonsil hypertrophy. CONCLUSION: In our study, the GAS carriage rate was similar to other reports, and GAS carrier state was not correlated with recurrent tonsillitis.
Authors: Jennifer M Dan; Colin Havenar-Daughton; Kayla Kendric; Rita Al-Kolla; Kirti Kaushik; Sandy L Rosales; Ericka L Anderson; Christopher N LaRock; Pandurangan Vijayanand; Grégory Seumois; David Layfield; Ramsey I Cutress; Christian H Ottensmeier; Cecilia S Lindestam Arlehamn; Alessandro Sette; Victor Nizet; Marcella Bothwell; Matthew Brigger; Shane Crotty Journal: Sci Transl Med Date: 2019-02-06 Impact factor: 17.956