| Literature DB >> 27259745 |
Carla Santos1, Chris Phillips2, A Gomez-Tato3, J Alvarez-Dios3, Ángel Carracedo2,4, Maria Victoria Lareu2.
Abstract
Three approaches applicable to the analysis of forensic ancestry-informative marker data-STRUCTURE, principal component analysis, and the Snipper Bayesian classification system-are reviewed. Detailed step-by-step guidance is provided for adjusting parameter settings in STRUCTURE with particular regard to their effect when differentiating populations. Several enhancements to the Snipper online forensic classification portal are described, highlighting the added functionality they bring to particular aspects of ancestry-informative SNP analysis in a forensic context.Keywords: Bayesian methods; Genetic ancestry; PCA; Reference data; SPSmart browser; STRUCTURE; Snipper
Mesh:
Year: 2016 PMID: 27259745 DOI: 10.1007/978-1-4939-3597-0_19
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745