Literature DB >> 27259503

Enhanced cosyntropin stimulation test performance enabled by electronic medical record.

Anat Ben-Shlomo1, Joseph Guzman2, James Mirocha3.   

Abstract

PURPOSE: To improve performance of the cosyntropin stimulation test (CST) used for diagnosis of adrenal-cortisol insufficiency by implementing an electronic medical record (EMR) system protocol.
METHODS: We implemented a SmartForm protocol of the validated CST in our EMR system (CS-Link™, EPIC) system and compared medical staff test performance before and after protocol implementation.
RESULTS: Correct performance of the CST improved significantly after EMR implementation. The number of correctly performed CSTs increased from 16.1 % before to 53.5 % after implementation (p < 0.0001) while those performed incorrectly and were uninterpretable decreased from 36.2 to 7.1 % (p < 0.0001). This performance improvement result in a calculated cost savings of $50,414 for every 100 tests performed.
CONCLUSIONS: The EMR system is useful for guiding medical staff to accurately perform the CST, reduce the number of wasted tests, and maximize staff time and resources.

Entities:  

Keywords:  Adrenal cortisol insufficiency; Cosyntropin stimulation test; Electronic medical record; Performance improvement

Mesh:

Substances:

Year:  2016        PMID: 27259503     DOI: 10.1007/s11102-016-0731-4

Source DB:  PubMed          Journal:  Pituitary        ISSN: 1386-341X            Impact factor:   4.107


  15 in total

1.  Assessment of adrenal function in cirrhotic patients using concentration of serum-free and salivary cortisol.

Authors:  Thierry Thevenot; Sophie Borot; Agnès Remy-Martin; Remy Sapin; Jean-Paul Cervoni; Carine Richou; Claire Vanlemmens; Denis Cleau; Emilie Muel; Anne Minello; Simona Tirziu; Alfred Penfornis; Vincent Di Martino; Elisabeth Monnet
Journal:  Liver Int       Date:  2011-01-13       Impact factor: 5.828

2.  Short Synacthen test versus insulin stress test for assessment of the hypothalamo [correction of hypothalmo]-pituitary--adrenal axis: controversy revisited.

Authors:  R N Clayton
Journal:  Clin Endocrinol (Oxf)       Date:  1996-02       Impact factor: 3.478

3.  Clinical factors associated with biochemical adrenal-cortisol insufficiency in hospitalized patients.

Authors:  Stephanie M Gwin; Annika K Khine; Anat Ben-Shlomo; James Mirocha; Ning-Ai Liu; Renee C Sheinin; Shlomo Melmed
Journal:  Am J Med       Date:  2014-03-13       Impact factor: 4.965

4.  Criteria for distinguishing normal from subnormal adrenocortical function using the Synacthen test.

Authors:  W R Greig; J D Maxwell; J A Boyle; R M Lindsay; M C Browning
Journal:  Postgrad Med J       Date:  1969-05       Impact factor: 2.401

Review 5.  Clinical review 62: Laboratory assessment of adrenal insufficiency.

Authors:  S K Grinspoon; B M Biller
Journal:  J Clin Endocrinol Metab       Date:  1994-10       Impact factor: 5.958

6.  Reliability of the 30-minute ACTH test in assessing hypothalamic-pituitary-adrenal function.

Authors:  J Lindholm; H Kehlet; M Blichert-Toft; B Dinesen; J Riishede
Journal:  J Clin Endocrinol Metab       Date:  1978-08       Impact factor: 5.958

7.  Re-evaluation of the clinical value of the 30 min ACTH test in assessing the hypothalamic-pituitary-adrenocortical function.

Authors:  J Lindholm; H Kehlet
Journal:  Clin Endocrinol (Oxf)       Date:  1987-01       Impact factor: 3.478

8.  Adrenal function in sepsis: the retrospective Corticus cohort study.

Authors:  Diane Lipiner-Friedman; Charles L Sprung; Pierre François Laterre; Yoram Weiss; Sergey V Goodman; Michael Vogeser; Josef Briegel; Didier Keh; Mervyn Singer; Rui Moreno; Eric Bellissant; Djillali Annane
Journal:  Crit Care Med       Date:  2007-04       Impact factor: 7.598

Review 9.  Diagnosis of adrenal insufficiency.

Authors:  Richard I Dorin; Clifford R Qualls; Lawrence M Crapo
Journal:  Ann Intern Med       Date:  2003-08-05       Impact factor: 25.391

Review 10.  Adrenal insufficiency in critical illness.

Authors:  Mark Stuart Cooper; Paul Michael Stewart
Journal:  J Intensive Care Med       Date:  2007 Nov-Dec       Impact factor: 3.510

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  1 in total

Review 1.  Investigation of the Hypothalamo-pituitary-adrenal (HPA) axis: a contemporary synthesis.

Authors:  Zuleyha Karaca; Ashley Grossman; Fahrettin Kelestimur
Journal:  Rev Endocr Metab Disord       Date:  2021-03-26       Impact factor: 6.514

  1 in total

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