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Literature DB >> 2725827

Is a certain amount of cysteine prerequisite to produce brain damage in neonatal rats?

Abstract

In this study, various manipulations were used to determine if certain amounts of cysteine are essential to damage the neonatal rat brain. The information gathered from this study indicated that concentration of free cysteine may be 0.6 mumol/g of wet brain weight or more to cause the toxicity to produce the brain damage, and the results were discussed in the light that free cysteine might itself be the cause of brain damage.

Entities: Chemical Disease Species

Mesh：

Substances：
Cysteine

Year: 1989 PMID： 2725827 DOI： 10.1007/bf00971320

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

19 in total

1. Acidic amino acids with strong excitatory actions on mammalian neurones.

Authors: D R CURTIS; J C WATKINS
Journal: J Physiol Date: 1963-04 Impact factor: 5.182

2. A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids.

Authors: M K Gaitonde
Journal: Biochem J Date: 1967-08 Impact factor: 3.857

3. Chlorpromazine and GABA.

Authors: H C Agrawal; J M Davis; E E Haynes; W A Himwich
Journal: Ann N Y Acad Sci Date: 1969-09-30 Impact factor: 5.691

4. Amino acids as putative transmitters: failure to bind to synaptic vesicles of guinea pig cerebral cortex.

Authors: D K Rassin
Journal: J Neurochem Date: 1972-01 Impact factor: 5.372

5. High-affinity glutamic acid binding to brain synaptic membranes.

Authors: E K Michaelis; M L Michaelis; L L Boyarsky
Journal: Biochim Biophys Acta Date: 1974-11-15

6. Cystathioninuria.

Authors: K N Shaw; E Lieberman; R Koch; G N Donnell
Journal: Am J Dis Child Date: 1967-01

7. An evaluation of selected brain constituents as putative excitatory neurotransmitters.

Authors: A Luini; N Tal; O Goldberg; V I Teichberg
Journal: Brain Res Date: 1984-12-24 Impact factor: 3.252

8. Development and other aspects of [35S]cysteine transport by rat brain synaptosomes.

Authors: S M Hwang; S Segal
Journal: J Neurochem Date: 1979-12 Impact factor: 5.372

9. High-affinity uptake system for cysteine in crude synaptosomal fractions of rat cerebral cortex.

Authors: C H Misra
Journal: J Neurosci Res Date: 1980 Impact factor: 4.164

10. Hallervorden-Spatz disease: cysteine accumulation and cysteine dioxygenase deficiency in the globus pallidus.

Authors: T L Perry; M G Norman; V W Yong; S Whiting; J U Crichton; S Hansen; S J Kish
Journal: Ann Neurol Date: 1985-10 Impact factor: 10.422

8 in total

Review 1. Mechanisms of L-cysteine neurotoxicity.

Authors: R Janáky; V Varga; A Hermann; P Saransaari; S S Oja
Journal: Neurochem Res Date: 2000-10 Impact factor: 3.996

2. Interaction of L-cysteine with a human excitatory amino acid transporter.

Authors: N Zerangue; M P Kavanaugh
Journal: J Physiol Date: 1996-06-01 Impact factor: 5.182

3. Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor.

Authors: S A Lipton; W K Kim; Y B Choi; S Kumar; D M D'Emilia; P V Rayudu; D R Arnelle; J S Stamler
Journal: Proc Natl Acad Sci U S A Date: 1997-05-27 Impact factor: 11.205

4. Rapid determination of cysteine and chiral discrimination of D-/L-cysteine via the aggregation-induced emission enhancement of gold nanoclusters by Ag^.

Authors: Shengli Ruan; Yan Zhou; Min Zhang; Hongyang Zhang; Yuerong Wang; Ping Hu
Journal: Anal Sci Date: 2022-04-01 Impact factor: 2.081

5. S-sulfo-cysteine is an endogenous amino acid in neonatal rat brain but an unlikely mediator of cysteine neurotoxicity.

Authors: Abdul-Karim Abbas; Wanlin Xia; Mattias Tranberg; Holger Wigström; Stephen G Weber; Mats Sandberg
Journal: Neurochem Res Date: 2007-09-01 Impact factor: 3.996