Correction: Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition.

[This corrects the article DOI: 10.1371/journal.pgen.1005982.].

Some ORF names, lengths and mutations in Table 1 are incorrect. Specifically, the ORF names and ORF lengths listed for the paqr-2(et36) and paqr-2(et35) alleles, and the ORF names and mutations listed for the iglr-2(et34), iglr-2(et37) and iglr-2(et38) alleles. The shift by one amino acid position in the mutation column also applies to the iglr-2 mutations indicated in Fig 2. Please see the corrected Table 1 and Fig 2 here.

Table 1

Description of the novel paqr-2 and iglr-2 alleles.

Gene(allele)	ORF name	ORF length	Mutation
paqr-2(et36)	Y32H12A.5	581 aa	D(GAT)282N(AAT)
paqr-2(et35)	Y32H12A.5	581 aa	G(GGA)533R(AGA)
iglr-2(et34)	ZC262.3a	773 aa	W(TGG)84STOP(TAG)
iglr-2(et37)	ZC262.3a	773 aa	G(GGT)498D(GAT)
iglr-2(et38)	ZC262.3a	773 aa	Q(CAA)594STOP(TAA)

Fig 2

Novel alleles of PAQR-2 and IGLR-2, and interaction of IGLR-2 with PAQR-2.

(A) Schematic structures of the IGLR-2 and PAQR-2 proteins, with novel mutations indicated by red arrowheads. The VC155 and VN173 fragments added to the C and N terminal ends of IGLR-2 and PAQR-2, respectively, allows reconstitution of a full and fluorescent VENUS YFP protein if the two proteins come into close proximity. (B) Result of the BiFC experiment showing that IGLR-2 and PAQR-2 contact each other on cellular membranes. The top two panels show a transgenic worm co-expressing the fusion proteins depicted in (A); note the clear membrane-localized fluorescence indicative of IGLR-2 and PAQR-2 interaction. The middle two panels show a transgenic worm co-expressing the tagged IGLR-2 and a tagged PAQR-1 protein; note that only autofluorescent gut granules emit a signal, indicating that IGLR-2 and PAQR-1 do not interact with each other. The bottom two panels show a transgenic animal carrying the two empty vectors used in the BiFC experiments; note again that only autofluorescent gut granules emit a signal.