Literature DB >> 27257811

Correction: Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.

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Abstract

[This corrects the article DOI: 10.1371/journal.pone.0154413.].

Entities:  

Year:  2016        PMID: 27257811      PMCID: PMC4892495          DOI: 10.1371/journal.pone.0157283

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


In Fig 2, the labels for the individual stains are missing. Please see the corrected Fig 2 here. The publisher apologizes for the error.
Fig 2

Tbx18 LOF phenotype in P0 UGS.

(A-I) H&E stains of P0 urogenital sinuses. (A-C) Wild type histology shows high cell density in the mesenchyme surrounding the epithelial prostate buds (A, B), and urethral epithelium is composed of 4–6 cell layers with a smooth apical surface (C). (D-F) 12Gso/Tbx18 compound heterozygotes present an intermediate phenotype in the UGS mesenchyme and the urethral epithelium. (G-I) Tbx18 mutants have very low mesenchymal cell density surrounding epithelial prostate buds. The urethral epithelium in these mutants is increased in thickness with larger cell volumes (compare arrows in C, F, and I). (J) Measurements of the epithelial thickness in the urethral epithelium. The epithelium on the dorsal side is significantly increased in thickness compared to wild type littermates.

Tbx18 LOF phenotype in P0 UGS.

(A-I) H&E stains of P0 urogenital sinuses. (A-C) Wild type histology shows high cell density in the mesenchyme surrounding the epithelial prostate buds (A, B), and urethral epithelium is composed of 4–6 cell layers with a smooth apical surface (C). (D-F) 12Gso/Tbx18 compound heterozygotes present an intermediate phenotype in the UGS mesenchyme and the urethral epithelium. (G-I) Tbx18 mutants have very low mesenchymal cell density surrounding epithelial prostate buds. The urethral epithelium in these mutants is increased in thickness with larger cell volumes (compare arrows in C, F, and I). (J) Measurements of the epithelial thickness in the urethral epithelium. The epithelium on the dorsal side is significantly increased in thickness compared to wild type littermates.
  1 in total

1.  Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.

Authors:  C Chase Bolt; Soumya Negi; Nuno Guimarães-Camboa; Huimin Zhang; Joseph M Troy; Xiaochen Lu; Andreas Kispert; Sylvia M Evans; Lisa Stubbs
Journal:  PLoS One       Date:  2016-04-27       Impact factor: 3.240

  1 in total

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