Literature DB >> 27257759

Human Pluripotent Stem Cells: Myths and Future Realities for Liver Cell Therapy.

Orit Goldman1, Valerie Gouon-Evans2.   

Abstract

The severe shortage of organ donors for treating patients with liver disease has prompted in vitro efforts to produce the main functional cells of the liver: hepatocyte-like cells (Hep cells). We consider the key challenges posed by various stem cell technologies and liver pathologies for developing clinically useful Hep cells.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27257759     DOI: 10.1016/j.stem.2016.05.019

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  6 in total

1.  Wound healing and fibrosis: current stem cell therapies.

Authors:  Ruth Ellen Jones; Deshka S Foster; Michael S Hu; Michael T Longaker
Journal:  Transfusion       Date:  2019-02       Impact factor: 3.157

2.  Endothelial cell-derived matrix promotes the metabolic functional maturation of hepatocyte via integrin-Src signalling.

Authors:  Xinyue Guo; Weihong Li; Minghui Ma; Xin Lu; Haiyan Zhang
Journal:  J Cell Mol Med       Date:  2017-05-04       Impact factor: 5.310

3.  Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions.

Authors:  Zhongwen Li; Jun Wu; Lei Wang; Weifang Han; Juan Yu; Xin Liu; Yukai Wang; Ying Zhang; Guihai Feng; Wei Li; Glyn Nigel Stacey; Qi Gu; Baoyang Hu; Liu Wang; Qi Zhou; Jie Hao
Journal:  Cell Death Dis       Date:  2019-10-10       Impact factor: 8.469

4.  3D culture of functional human iPSC-derived hepatocytes using a core-shell microfiber.

Authors:  Shogo Nagata; Fumisato Ozawa; Minghao Nie; Shoji Takeuchi
Journal:  PLoS One       Date:  2020-06-11       Impact factor: 3.240

Review 5.  In Vitro Generated Hepatocyte-Like Cells: A Novel Tool in Regenerative Medicine and Drug Discovery.

Authors:  Kobra Zakikhan; Behshad Pournasr; Massoud Vosough; Marjan Nassiri-Asl
Journal:  Cell J       Date:  2017-02-22       Impact factor: 2.479

6.  Autologous and Heterologous Cell Therapy for Hemophilia B toward Functional Restoration of Factor IX.

Authors:  Suvasini Ramaswamy; Nina Tonnu; Tushar Menon; Benjamin M Lewis; Kevin T Green; Derek Wampler; Paul E Monahan; Inder M Verma
Journal:  Cell Rep       Date:  2018-05-01       Impact factor: 9.423

  6 in total

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