Literature DB >> 27257758

Closing in on Mass Production of Mature Human Beta Cells.

Timothy J Kieffer1.   

Abstract

Human pluripotent stem cell differentiation protocols based on mimicking developmental pathways are getting close to generating fully fledged pancreatic endocrine cells, including insulin-producing beta cells. However, challenges remain in identifying pathways to trigger the attainment of robust glucose responsiveness that occurs postnatally in beta cells.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27257758     DOI： 10.1016/j.stem.2016.05.014

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  19 in total

1.  Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.

Authors:  Chen Huang; Emily M Walker; Prasanna K Dadi; Ruiying Hu; Yanwen Xu; Wenjian Zhang; Tiziana Sanavia; Jisoo Mun; Jennifer Liu; Gopika G Nair; Hwee Yim Angeline Tan; Sui Wang; Mark A Magnuson; Christian J Stoeckert; Matthias Hebrok; Maureen Gannon; Weiping Han; Roland Stein; David A Jacobson; Guoqiang Gu
Journal:  Dev Cell       Date:  2018-04-12       Impact factor: 12.270

Review 2.  Towards stem cell therapies for skeletal muscle repair.

Authors:  Robert N Judson; Fabio M V Rossi
Journal:  NPJ Regen Med       Date:  2020-05-11

3.  Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors.

Authors:  Nicole A J Krentz; Dennis van Hoof; Zhongmei Li; Akie Watanabe; Mei Tang; Cuilan Nian; Michael S German; Francis C Lynn
Journal:  Dev Cell       Date:  2017-04-24       Impact factor: 12.270

Review 4.  Advances in islet encapsulation technologies.

Authors:  Tejal Desai; Lonnie D Shea
Journal:  Nat Rev Drug Discov       Date:  2016-12-23       Impact factor: 84.694

Review 5.  Regenerative medicine and cell-based approaches to restore pancreatic function.

Authors:  Cara Ellis; Adam Ramzy; Timothy J Kieffer
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2017-08-16       Impact factor: 46.802

6.  Engineering Mammalian Cells to Control Glucose Homeostasis.

Authors:  Jiawei Shao; Xinyuan Qiu; Mingqi Xie
Journal:  Methods Mol Biol       Date:  2021

Review 7.  Rebuilding a better home for transplanted islets.

Authors:  Daniel M Tremmel; Jon S Odorico
Journal:  Organogenesis       Date:  2018-09-25       Impact factor: 2.500

Review 8.  Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.

Authors:  Jon Odorico; James Markmann; Douglas Melton; Julia Greenstein; Albert Hwa; Cristina Nostro; Alireza Rezania; Jose Oberholzer; Daniel Pipeleers; Luhan Yang; Chad Cowan; Danwei Huangfu; Dieter Egli; Uri Ben-David; Ludovic Vallier; Shane T Grey; Qizhi Tang; Bart Roep; Camilo Ricordi; Ali Naji; Giuseppe Orlando; Daniel G Anderson; Mark Poznansky; Barbara Ludwig; Alice Tomei; Dale L Greiner; Melanie Graham; Melissa Carpenter; Giovanni Migliaccio; Kevin D'Amour; Bernhard Hering; Lorenzo Piemonti; Thierry Berney; Mike Rickels; Thomas Kay; Ann Adams
Journal:  Transplantation       Date:  2018-08       Impact factor: 4.939

Review 9.  Human pluripotent stem cell-derived insulin-producing cells: A regenerative medicine perspective.

Authors:  Adriana Migliorini; Maria Cristina Nostro; Julie B Sneddon
Journal:  Cell Metab       Date:  2021-04-06       Impact factor: 27.287

10.  Temporal Transcriptome Analysis Reveals Dynamic Gene Expression Patterns Driving β-Cell Maturation.

Authors:  Tiziana Sanavia; Chen Huang; Elisabetta Manduchi; Yanwen Xu; Prasanna K Dadi; Leah A Potter; David A Jacobson; Barbara Di Camillo; Mark A Magnuson; Christian J Stoeckert; Guoqiang Gu
Journal:  Front Cell Dev Biol       Date:  2021-05-04
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