Literature DB >> 27257752

Treating Liver Fibrosis: (Re)Programmed to Succeed.

Yuan Guan1, Dan Xu1, Gary Peltz2.   

Abstract

Two papers (Rezvani et al., 2016; Song et al., 2016) in this issue of Cell Stem Cell use transcription-factor-mediated reprogramming to convert liver myofibroblasts into hepatocyte-like cells in mice. Moreover, murine models of fibrotic and cholestatic liver injury were used to demonstrate that this approach has potential for treatment of liver cirrhosis.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27257752     DOI: 10.1016/j.stem.2016.05.007

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  1 in total

1.  The therapeutic potential of induced hepatocyte-like cells generated by direct reprogramming on hepatic fibrosis.

Authors:  Suhyun Park; Seon In Hwang; Jonghun Kim; Seoyeon Hwang; Sohee Kang; Sera Yang; Jonghwa Kim; Wonseok Kang; Kyun-Hwan Kim; Dong Wook Han; Yong-Han Paik
Journal:  Stem Cell Res Ther       Date:  2019-01-11       Impact factor: 6.832

  1 in total

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