Literature DB >> 27256556

Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression.

Anthony A Grace1.   

Abstract

The dopamine system is unique among the brain's modulatory systems in that it has discrete projections to specific brain regions involved in motor behaviour, cognition and emotion. Dopamine neurons exhibit several activity patterns - including tonic and phasic firing - that are determined by a combination of endogenous pacemaker conductances and regulation by multiple afferent systems. Emerging evidence suggests that disruptions in these regulatory systems may underlie the pathophysiology of several psychiatric disorders, including schizophrenia and depression.

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Year:  2016        PMID： 27256556      PMCID： PMC5166560          DOI： 10.1038/nrn.2016.57

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN： 1471-003X            Impact factor:   34.870


  114 in total

1.  Dopamine attenuates prefrontal cortical suppression of sensory inputs to the basolateral amygdala of rats.

Authors:  J A Rosenkranz; A A Grace
Journal:  J Neurosci       Date:  2001-06-01       Impact factor: 6.167

2.  Pathogenesis of schizophrenia: a psychopathological perspective.

Authors:  D G Cunningham Owens; Patrick Miller; Stephen M Lawrie; Eve C Johnstone
Journal:  Br J Psychiatry       Date:  2005-05       Impact factor: 9.319

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Authors:  E Lynd-Balta; S N Haber
Journal:  Neuroscience       Date:  1994-04       Impact factor: 3.590

4.  Long-term administration of d-amphetamine: progressive augmentation of motor activity and stereotypy.

Authors:  D S Segal; A J Mandell
Journal:  Pharmacol Biochem Behav       Date:  1974 Mar-Apr       Impact factor: 3.533

Review 5.  Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient.

Authors:  S Kapur; G Remington
Journal:  Biol Psychiatry       Date:  2001-12-01       Impact factor: 13.382

Review 6.  Neurobiological basis of depression: an update.

Authors:  Madhu Kalia
Journal:  Metabolism       Date:  2005-05       Impact factor: 8.694

Review 7.  Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.

Authors:  Satoshi Ikemoto
Journal:  Brain Res Rev       Date:  2007-05-17

8.  Peripubertal diazepam administration prevents the emergence of dopamine system hyperresponsivity in the MAM developmental disruption model of schizophrenia.

Authors:  Yijuan Du; Anthony A Grace
Journal:  Neuropsychopharmacology       Date:  2013-04-23       Impact factor: 7.853

9.  Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo.

Authors:  K Chergui; P J Charléty; H Akaoka; C F Saunier; J L Brunet; M Buda; T H Svensson; G Chouvet
Journal:  Eur J Neurosci       Date:  1993-02-01       Impact factor: 3.386

10.  Opioid modulation of ventral pallidal afferents to ventral tegmental area neurons.

Authors:  Gregory O Hjelmstad; Yanfang Xia; Elyssa B Margolis; Howard L Fields
Journal:  J Neurosci       Date:  2013-04-10       Impact factor: 6.167
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  270 in total

Review 1.  Dopamine tunes prefrontal outputs to orchestrate aversive processing.

Authors:  Caitlin M Vander Weele; Cody A Siciliano; Kay M Tye
Journal:  Brain Res       Date:  2018-12-01       Impact factor: 3.252

2.  Age-Related Trajectories of Functional Coupling between the VTA and Nucleus Accumbens Depend on Motivational State.

Authors:  Vishnu P Murty; Hemali Shah; David Montez; Will Foran; Finnegan Calabro; Beatriz Luna
Journal:  J Neurosci       Date:  2018-07-20       Impact factor: 6.167

3.  A Perceptual Inference Mechanism for Hallucinations Linked to Striatal Dopamine.

Authors:  Clifford M Cassidy; Peter D Balsam; Jodi J Weinstein; Rachel J Rosengard; Mark Slifstein; Nathaniel D Daw; Anissa Abi-Dargham; Guillermo Horga
Journal:  Curr Biol       Date:  2018-02-02       Impact factor: 10.834

4.  Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites.

Authors:  Changliang Liu; Lauren Kershberg; Jiexin Wang; Shirin Schneeberger; Pascal S Kaeser
Journal:  Cell       Date:  2018-02-01       Impact factor: 41.582

Review 5.  Overlap in the neural circuitry and molecular mechanisms underlying ketamine abuse and its use as an antidepressant.

Authors:  Saurabh S Kokane; Ross J Armant; Carlos A Bolaños-Guzmán; Linda I Perrotti
Journal:  Behav Brain Res       Date:  2020-02-13       Impact factor: 3.332

Review 6.  Electrical stimulation of cranial nerves in cognition and disease.

Authors:  Devin Adair; Dennis Truong; Zeinab Esmaeilpour; Nigel Gebodh; Helen Borges; Libby Ho; J Douglas Bremner; Bashar W Badran; Vitaly Napadow; Vincent P Clark; Marom Bikson
Journal:  Brain Stimul       Date:  2020-02-23       Impact factor: 8.955

7.  Dopamine D2L Receptor Deficiency Causes Stress Vulnerability through 5-HT1A Receptor Dysfunction in Serotonergic Neurons.

Authors:  Norifumi Shioda; Yoshiki Imai; Yasushi Yabuki; Wataru Sugimoto; Kouya Yamaguchi; Yanyan Wang; Takatoshi Hikida; Toshikuni Sasaoka; Michihiro Mieda; Kohji Fukunaga
Journal:  J Neurosci       Date:  2019-08-01       Impact factor: 6.167

8.  Female rats are resistant to the long-lasting neurobehavioral changes induced by adolescent stress exposure.

Authors:  Katharina Klinger; Felipe V Gomes; Millie Rincón-Cortés; Anthony A Grace
Journal:  Eur Neuropsychopharmacol       Date:  2019-07-29       Impact factor: 4.600

9.  Repositioning Dopamine D2 Receptor Agonist Bromocriptine to Enhance Docetaxel Chemotherapy and Treat Bone Metastatic Prostate Cancer.

Authors:  Yang Yang; Kenza Mamouni; Xin Li; Yanhua Chen; Sravan Kavuri; Yuhong Du; Haian Fu; Omer Kucuk; Daqing Wu
Journal:  Mol Cancer Ther       Date:  2018-06-15       Impact factor: 6.261

10.  Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions.

Authors:  Amaia M Erdozain; Stéphanie De Gois; Véronique Bernard; Victor Gorgievski; Nicolas Pietrancosta; Sylvie Dumas; Carlos E Macedo; Peter Vanhoutte; Jorge E Ortega; J Javier Meana; Eleni T Tzavara; Vincent Vialou; Bruno Giros
Journal:  Neuropsychopharmacology       Date:  2017-09-14       Impact factor: 7.853
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