Literature DB >> 27256366

Thyroid cartilage invasion in laryngeal and hypopharyngeal squamous cell carcinoma treated with total laryngectomy.

Mario Koopmann1, Daniel Weiss2, Matthias Steiger3, Sandra Elges4, Claudia Rudack2, Markus Stenner2.   

Abstract

The objective of this study is to analyze the accuracy of computed tomography in detecting malignant thyroid cartilage invasion. In a retrospective chart review, 120 patients with carcinoma of the larynx and hypopharynx underwent computed tomography before total laryngectomy. These data were compared with the histological specimens. Multidetector computed tomography (MDCT) scan had a positive predictive value (PPV) of 76 % and a negative predictive value (NPV) of 69 %. The specificity of MDCT was 89 % and sensitivity was 46 %. Comparison between radiologic suspected cartilage invasion and histologic results showed a significant correlation (p < 0.02). We found no significant impact of cartilage invasion concerning survival rates (5-year overall survival p = 0.683; 5-year disease-free survival p = 0.711). Preoperative CT scan is an important instrument in detecting neoplastic cartilage invasion.

Entities:  

Keywords:  Cartilage invasion; Hypopharyngeal; Laryngeal; Negative predictive value; Positive predictive value; Prognosis; Sensitivity; Specificity; Squamous cell carcinoma

Mesh：

Year:  2016        PMID： 27256366     DOI： 10.1007/s00405-016-4120-4

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN： 0937-4477            Impact factor:   2.503


  21 in total

1.  Pretherapeutic staging of hypopharyngeal carcinoma. Clinical findings, computed tomography, and magnetic resonance imaging compared with histopathologic evaluation.

Authors:  P Zbären; M Becker; H Läng
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1997-09

2.  Overstaging of cartilage invasion by multidetector CT scan for laryngeal cancer and its potential effect on the use of organ preservation with chemoradiation.

Authors:  B Li; M Bobinski; R Gandour-Edwards; D G Farwell; A M Chen
Journal:  Br J Radiol       Date:  2010-09-21       Impact factor: 3.039

3.  Organ preservation surgery for laryngeal squamous cell carcinoma: low incidence of thyroid cartilage invasion.

Authors:  Dana M Hartl; Guillaume Landry; Stéphane Hans; Patrick Marandas; Daniel F Brasnu
Journal:  Laryngoscope       Date:  2010-06       Impact factor: 3.325

4.  Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen.

Authors:  Jean-François Daisne; Thierry Duprez; Birgit Weynand; Max Lonneux; Marc Hamoir; Hervé Reychler; Vincent Grégoire
Journal:  Radiology       Date:  2004-08-18       Impact factor: 11.105

5.  A morphometric comparison of the changes in the laryngeal skeleton associated with invasion by tumor and by external-beam radiation.

Authors:  C L Dyess; D Carter; J A Kirchner; R E Baron
Journal:  Cancer       Date:  1987-03-15       Impact factor: 6.860

6.  Outcomes following total laryngectomy for squamous cell carcinoma: one centre experience.

Authors:  S C Leong; S-S Kartha; C Kathan; J Sharp; S Mortimore
Journal:  Eur Ann Otorhinolaryngol Head Neck Dis       Date:  2012-08-24       Impact factor: 2.080

7.  Pretherapeutic staging of laryngeal carcinoma. Clinical findings, computed tomography, and magnetic resonance imaging compared with histopathology.

Authors:  P Zbären; M Becker; H Läng
Journal:  Cancer       Date:  1996-04-01       Impact factor: 6.860

8.  Neoplastic infiltration of laryngeal cartilages: histocytochemical study.

Authors:  A Gallo; P Mocetti; M De Vincentiis; M Simonelli; S Ciampini; P Bianco; E Bonucci
Journal:  Laryngoscope       Date:  1992-08       Impact factor: 3.325

Review 9.  Staging of laryngeal and hypopharyngeal cancer: value of imaging studies.

Authors:  Robert Hermans
Journal:  Eur Radiol       Date:  2006-05-30       Impact factor: 7.034

10.  Pathologic assessment of computerized tomography accuracy for the evaluation of the laryngeal cartilaginous framework in laryngopharyngeal carcinomas.

Authors:  S Sulfaro; F Querin; L Barzan; M Lutman; R Comoretto; R Volpe; A Carbone
Journal:  Tumori       Date:  1989-04-30
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  2 in total

1.  Imaging Accuracy in Preoperative Staging of T3-T4 Laryngeal Cancers.

Authors:  Marco Benazzo; Fabio Sovardi; Lorenzo Preda; Simone Mauramati; Sergio Carnevale; Giulia Bertino; Francesca Berton; Matteo Meroni; Irene Herman; Giuseppe Trisolini; Patrizia Morbini
Journal:  Cancers (Basel)       Date:  2020-04-26       Impact factor: 6.639

2.  Assessment of cartilage invasion in case of laryngeal cancer by means of longitudinal sectioning for histopathology - Clinical implications.

Authors:  Liucija Weselik; Ewa Majchrzak; Matthew Ibbs; Adam Lewandowski; Andrzej Marszałek; Piotr Machczyński; Wojciech Golusiński
Journal:  Rep Pract Oncol Radiother       Date:  2019-07-30
  2 in total

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