Yuta Fukushima1, Gakushi Yoshikawa2, Megumi Takasago2, Seiichiro Shimizu3, Kazuo Tsutsumi2. 1. Department of Neurosurgery, Showa General Hospital, Kodaira, Tokyo, Japan. Electronic address: fukushima-tky@umin.ac.jp. 2. Department of Neurosurgery, Showa General Hospital, Kodaira, Tokyo, Japan. 3. Department of Pathology, Showa General Hospital, Kodaira, Tokyo, Japan.
Abstract
BACKGROUND: Late brain metastasis from renal cell carcinoma (RCC), which is generally considered as metastasis occurring more than 10 years after nephrectomy, often occurs as a solitary lesion, and total resection is recommended to achieve remission. CASE DESCRIPTION: We describe a rare case of multiple late brain metastases from RCC in a 60-year-old man who presented with 3 brain metastases from RCC 22 years after nephrectomy. Total removal of the 3 lesions achieved remission without adjuvant therapy. CONCLUSIONS: Total removal of late brain metastasis from RCC, even occurring with multiple lesions, can achieve total remission under specific conditions.
BACKGROUND: Late brain metastasis from renal cell carcinoma (RCC), which is generally considered as metastasis occurring more than 10 years after nephrectomy, often occurs as a solitary lesion, and total resection is recommended to achieve remission. CASE DESCRIPTION: We describe a rare case of multiple late brain metastases from RCC in a 60-year-old man who presented with 3 brain metastases from RCC 22 years after nephrectomy. Total removal of the 3 lesions achieved remission without adjuvant therapy. CONCLUSIONS: Total removal of late brain metastasis from RCC, even occurring with multiple lesions, can achieve total remission under specific conditions.
Authors: Maria F Czyzyk-Krzeska; Julio A Landero Figueroa; Shuchi Gulati; John T Cunningham; Jarek Meller; Behrouz ShamsaeI; Bhargav Vemuri; David R Plas Journal: Genes (Basel) Date: 2021-03-09 Impact factor: 4.096