Literature DB >> 27255970

The Regulation of GluN2A by Endogenous and Exogenous Regulators in the Central Nervous System.

Yongjun Sun1,2, Liying Zhan1, Xiaokun Cheng3, Linan Zhang4, Jie Hu5, Zibin Gao6,7,8.   

Abstract

The NMDA receptor is the most widely studied ionotropic glutamate receptor, and it is central to many physiological and pathophysiological processes in the central nervous system. GluN2A is one of the two main types of GluN2 NMDA receptor subunits in the forebrain. The proper activity of GluN2A is important to brain function, as the abnormal regulation of GluN2A may induce some neuropsychiatric disorders. This review will examine the regulation of GluN2A by endogenous and exogenous regulators in the central nervous system.

Entities:  

Keywords:  Endogenous regulators; Exogenous regulators; GluN2A; Regulation

Mesh：

Substances：

Year:  2016        PMID： 27255970     DOI： 10.1007/s10571-016-0388-6

Source DB:  PubMed          Journal:  Cell Mol Neurobiol        ISSN： 0272-4340            Impact factor:   5.046


  208 in total

1.  Activity-dependent mRNA splicing controls ER export and synaptic delivery of NMDA receptors.

Authors:  Yuanyue Mu; Takeshi Otsuka; April C Horton; Derek B Scott; Michael D Ehlers
Journal:  Neuron       Date:  2003-10-30       Impact factor: 17.173

2.  PSD-95 eliminates Src-induced potentiation of NR1/NR2A-subtype NMDA receptor channels and reduces high-affinity zinc inhibition.

Authors:  Yasue Yamada; Takashi Iwamoto; Yoshifumi Watanabe; Kenji Sobue; Makoto Inui
Journal:  J Neurochem       Date:  2002-05       Impact factor: 5.372

3.  Local anaesthetics inhibit signalling of human NMDA receptors recombinantly expressed in Xenopus laevis oocytes: role of protein kinase C.

Authors:  K Hahnenkamp; M E Durieux; A Hahnenkamp; S K Schauerte; C W Hoenemann; V Vegh; G Theilmeier; M W Hollmann
Journal:  Br J Anaesth       Date:  2005-11-18       Impact factor: 9.166

4.  Dopamine D1 receptor-dependent trafficking of striatal NMDA glutamate receptors to the postsynaptic membrane.

Authors:  A W Dunah; D G Standaert
Journal:  J Neurosci       Date:  2001-08-01       Impact factor: 6.167

5.  TiO2 nanoparticle-induced neurotoxicity may be involved in dysfunction of glutamate metabolism and its receptor expression in mice.

Authors:  Xiao Ze; Mingyu Su; Xiaoyang Zhao; Hao Jiang; Jie Hong; Xiaohong Yu; Dong Liu; Bingqing Xu; Lei Sheng; Qiuping Zhou; Junling Zhou; Jingwen Cui; Kai Li; Ling Wang; Yuguan Ze; Fashui Hong
Journal:  Environ Toxicol       Date:  2014-11-20       Impact factor: 4.119

6.  Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus.

Authors:  M Roceri; W Hendriks; G Racagni; B A Ellenbroek; M A Riva
Journal:  Mol Psychiatry       Date:  2002       Impact factor: 15.992

7.  Increased expression of the NR2A NMDA receptor subunit in the prefrontal cortex of rats reared in isolation.

Authors:  Julia J Turnock-Jones; Carol A Jennings; Melanie J Robbins; Jane E Cluderay; Jackie Cilia; Juliet L Reid; Adam Taylor; Declan N C Jones; Piers C Emson; Eric Southam
Journal:  Synapse       Date:  2009-10       Impact factor: 2.562

8.  Morphine withdrawal affects both delayed-escape behaviour in Morris water maze and hippocampal NR2A/2B expression ratio.

Authors:  Zhifang Dong; Weixia Zhong; Meng Tian; Huili Han; Rongrong Mao; Jun Cao; Nan Sui; Tianle Xu; Jianhong Luo; Lin Xu
Journal:  Brain Res       Date:  2008-03-04       Impact factor: 3.252

9.  Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum.

Authors:  Emily L Jocoy; Véronique M André; Damian M Cummings; Shilpa P Rao; Nanping Wu; Amy J Ramsey; Marc G Caron; Carlos Cepeda; Michael S Levine
Journal:  Front Syst Neurosci       Date:  2011-05-11

10.  Trafficking of the NMDAR2B receptor subunit distal cytoplasmic tail from endoplasmic reticulum to the synapse.

Authors:  Steve Standley; Ronald S Petralia; Manneth Gravell; Rebecca Hamilton; Ya-Xian Wang; Manfred Schubert; Robert J Wenthold
Journal:  PLoS One       Date:  2012-06-27       Impact factor: 3.240
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  1 in total

1.  Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice.

Authors:  Naoko Morimura; Hiroki Yasuda; Kazuhiko Yamaguchi; Kei-Ichi Katayama; Minoru Hatayama; Naoko H Tomioka; Maya Odagawa; Akiko Kamiya; Yoshimi Iwayama; Motoko Maekawa; Kazuhiko Nakamura; Hideo Matsuzaki; Masatsugu Tsujii; Kazuyuki Yamada; Takeo Yoshikawa; Jun Aruga
Journal:  Nat Commun       Date:  2017-06-12       Impact factor: 14.919
  1 in total

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