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Literature DB >> 27255896

D-Peptides as Recognition Molecules and Therapeutic Agents.

Min Liu¹, Xue Li¹, Zuoxu Xie¹, Cao Xie¹, Changyou Zhan^1,2, Xuefeng Hu¹, Qing Shen¹, Xiaoli Wei¹, Bingxia Su¹, Jing Wang¹, Weiyue Lu¹.

Abstract

Over recent years, D-peptides have attracted increasing attention. D-peptides increase enzymatic stability, prolong the plasma half-life, improve oral bioavailability, and enhance binding activity and specificity with receptor or target proteins, in comparison with the corresponding L-peptide. Therefore, D-peptides are considered to have potential as recognition molecules and therapeutic agents. This review focuses on the design and application of D-peptides with biological activity.

Keywords: mirror-image phage display; molecular recognition; peptides; retro-inverso

Mesh：

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Year: 2016 PMID： 27255896 DOI： 10.1002/tcr.201600005

Source DB: PubMed Journal: Chem Rec ISSN： 1528-0691 Impact factor: 6.771

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Cited

17 in total

Review 1. Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease.

Authors: Isabelle Aillaud; Susanne Aileen Funke
Journal: Cell Mol Neurobiol Date: 2022-05-21 Impact factor: 5.046

Review 2. Recent advances in the discovery of senolytics.

Authors: Lei Zhang; Louise E Pitcher; Vaishali Prahalad; Laura J Niedernhofer; Paul D Robbins
Journal: Mech Ageing Dev Date: 2021-10-14 Impact factor: 5.432

3. Retro-inverso D-peptides as a novel targeted immunotherapy for Type 1 diabetes.

Authors: Angela Lombardi; Erlinda Concepcion; Hanxi Hou; Hanane Arib; Mihaly Mezei; Roman Osman; Yaron Tomer
Journal: J Autoimmun Date: 2020-09-17 Impact factor: 7.094

Review 4. Synthetic Biology and Computer-Based Frameworks for Antimicrobial Peptide Discovery.

Authors: Marcelo D T Torres; Jicong Cao; Octavio L Franco; Timothy K Lu; Cesar de la Fuente-Nunez
Journal: ACS Nano Date: 2021-02-04 Impact factor: 15.881

5. Nature of Fast Relaxation Processes and Spectroscopy of a Membrane-Active Peptide Modified with Fluorescent Amino Acid Exhibiting Excited State Intramolecular Proton Transfer and Efficient Stimulated Emission.

Authors: Yevgeniy O Shaydyuk; Nataliia V Bashmakova; Andriy M Dmytruk; Olexiy D Kachkovsky; Serhii Koniev; Alexander V Strizhak; Igor V Komarov; Kevin D Belfield; Mykhailo V Bondar; Oleg Babii
Journal: ACS Omega Date: 2021-04-05

6. Anti-Double-Stranded DNA IgG Participates in Renal Fibrosis through Suppressing the Suppressor of Cytokine Signaling 1 Signals.

Authors: Ping Wang; Jie Yang; Fang Tong; Zhaoyang Duan; Xingyin Liu; Linlin Xia; Ke Li; Yumin Xia
Journal: Front Immunol Date: 2017-05-31 Impact factor: 7.561

D-Peptides as Recognition Molecules and Therapeutic Agents.

Review 1. Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease.

Review 2. Recent advances in the discovery of senolytics.

3. Retro-inverso D-peptides as a novel targeted immunotherapy for Type 1 diabetes.

Review 4. Synthetic Biology and Computer-Based Frameworks for Antimicrobial Peptide Discovery.

5. Nature of Fast Relaxation Processes and Spectroscopy of a Membrane-Active Peptide Modified with Fluorescent Amino Acid Exhibiting Excited State Intramolecular Proton Transfer and Efficient Stimulated Emission.

6. Anti-Double-Stranded DNA IgG Participates in Renal Fibrosis through Suppressing the Suppressor of Cytokine Signaling 1 Signals.

7. MDP: A Deinococcus Mn2+-Decapeptide Complex Protects Mice from Ionizing Radiation.

Review 8. Roles of d-Amino Acids on the Bioactivity of Host Defense Peptides.

9. Efficacy of inverso isomer of CendR peptide on tumor tissue penetration.

10. Selective induction of cancer cell death by VDAC1-based peptides and their potential use in cancer therapy.