Hilmi R Dajani1, Kazuya Hosokawa2, Shin-Ichi Ando3. 1. School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, Canada. Electronic address: hdajani@eecs.uottawa.ca. 2. Department of Cardiovascular Medicine, Kyushu University Hospital, Fukuoka, Japan. 3. Sleep Apnea Center, Kyushu University Hospital, Fukuoka, Japan.
Abstract
BACKGROUND: Lung-to-finger circulation time of oxygenated blood during nocturnal periodic breathing in heart failure patients measured using polysomnography correlates negatively with cardiac function but possesses limited accuracy for cardiac output (CO) estimation. METHODS AND RESULTS: CO was recalculated from lung-to-finger circulation time using a multivariable linear model with information on age and average overnight heart rate in 25 patients who underwent evaluation of heart failure. The multivariable model decreased the percentage error to 22.3% relative to invasive CO measured during cardiac catheterization. CONCLUSIONS: This improved automated noninvasive CO estimation using multiple variables meets a recently proposed performance criterion for clinical acceptability of noninvasive CO estimation, and compares very favorably with other available methods.
BACKGROUND: Lung-to-finger circulation time of oxygenated blood during nocturnal periodic breathing in heart failurepatients measured using polysomnography correlates negatively with cardiac function but possesses limited accuracy for cardiac output (CO) estimation. METHODS AND RESULTS: CO was recalculated from lung-to-finger circulation time using a multivariable linear model with information on age and average overnight heart rate in 25 patients who underwent evaluation of heart failure. The multivariable model decreased the percentage error to 22.3% relative to invasive CO measured during cardiac catheterization. CONCLUSIONS: This improved automated noninvasive CO estimation using multiple variables meets a recently proposed performance criterion for clinical acceptability of noninvasive CO estimation, and compares very favorably with other available methods.