Literature DB >> 2725486

Analysis of a soluble lipid-protein complex carrying endogenous 11-cis retinaldehyde from bovine retinal pigment epithelium.

M A Livrea1, A Bongiorno, A Bono, L Tesoriere, M C Gueli, C Nicotra, L Pandolfo.   

Abstract

A soluble lipid-protein complex in bovine retinal pigment epithelium is shown to carry endogenous 11-cis retinaldehyde, in the extent of 15% of the total 11-cis retinaldehyde found in this tissue. The complex, analyzed with respect to its chemical composition, exhibits a lipid composition close resembling the lipid composition of the rod outer segment membrane; the SDS-PAGE evidences the presence of a number of protein bands, two of which of 34 and 27 kDa appear glycoproteins. Finally, the lipid-protein complex exhibits a discrete level of a Cathepsin D-like protease activity. From the above, the possibility is discussed that the soluble lipid-protein complex could represent some phagolysosomal inclusion occurring in the pigment epithelial cells upon rod outer segment phagocytosis.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2725486     DOI： 10.1007/bf00577113

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  23 in total

1.  Lipids of ocular tissues--X. Lipid composition of subcellular fractions of bovine retina.

Authors:  R E Anderson; M B Maude; W Zimmerman
Journal:  Vision Res       Date:  1975-10       Impact factor: 1.886

2.  THE ULTRASTRUCTURE OF THE PIGMENT EPITHELIUM AND OF THE PHOTORECEPTOR-PIGMENT EPITHELIUM JUNCTION IN THE HUMAN RETINA.

Authors:  A BAIRATI; N ORZALESI
Journal:  J Ultrastruct Res       Date:  1963-12

3.  The analysis of retinal isomers by high speed liquid chromatography.

Authors:  J P Rotmans; A Kropf
Journal:  Vision Res       Date:  1975-12       Impact factor: 1.886

4.  Occurrence of a binding protein for 11-cis-retinal in retina.

Authors:  S Futterman; J C Saari; S Blair
Journal:  J Biol Chem       Date:  1977-05-25       Impact factor: 5.157

5.  Investigation into the structural integrity of lysosomes in the normal and dystrophic rat retina.

Authors:  E M Burden; C M Yates; H W Reading; L Bitensky; J Chayen
Journal:  Exp Eye Res       Date:  1971-09       Impact factor: 3.467

6.  Fatty acid composition and pairing in phospholipids of rod outer segments.

Authors:  G P Miljanich; E A Dratz
Journal:  Methods Enzymol       Date:  1982       Impact factor: 1.600

7.  Analysis of geometrically isomeric vitamin A compounds.

Authors:  G W Groenendijk; P A Jansen; S L Bonting; F J Daemen
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

8.  Identification of the endogenous retinoids associated with three cellular retinoid-binding proteins from bovine retina and retinal pigment epithelium.

Authors:  J C Saari; L Bredberg; G G Garwin
Journal:  J Biol Chem       Date:  1982-11-25       Impact factor: 5.157

9.  Vitamin A transport between retina and pigment epithelium--an interstitial protein carrying endogenous retinol (interstitial retinol-binding protein).

Authors:  G I Liou; C D Bridges; S L Fong; R A Alvarez; F Gonzalez-Fernandez
Journal:  Vision Res       Date:  1982       Impact factor: 1.886
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.