Literature DB >> 27250640

Enantiomeric two-armed lanthanide-binding tags for complementary effects in paramagnetic NMR spectroscopy.

Michael D Lee1, Matthew L Dennis, James D Swarbrick, Bim Graham.   

Abstract

Two-armed lanthanide-binding tags induce significant, long-range paramagnetic effects in the NMR spectra of attached proteins. An enantiomeric pair of rigid, two-armed, cyclen-based tags are reported that produce markedly different effects from the same tagging site, allowing for the measurement of complementary paramagnetic restraints for structural studies.

Entities:  

Year:  2016        PMID： 27250640     DOI： 10.1039/c6cc02325h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Characterizing the magnetic susceptibility tensor of lanthanide-containing polymethylated-DOTA complexes.

Authors:  Madeleine Strickland; Charles D Schwieters; Christoph Göbl; Ana C L Opina; Marie-Paule Strub; Rolf E Swenson; Olga Vasalatiy; Nico Tjandra
Journal:  J Biomol NMR       Date:  2016-09-22       Impact factor: 2.835

2.  Sequence-specific assignment of methyl groups from the neuronal SNARE complex using lanthanide-induced pseudocontact shifts.

Authors:  Yun-Zu Pan; Bradley Quade; Kyle D Brewer; Monika Szabo; James D Swarbrick; Bim Graham; Josep Rizo
Journal:  J Biomol NMR       Date:  2016-12-17       Impact factor: 2.835

Review 3.  Paramagnetic NMR in drug discovery.

Authors:  Charlotte A Softley; Mark J Bostock; Grzegorz M Popowicz; Michael Sattler
Journal:  J Biomol NMR       Date:  2020-06-10       Impact factor: 2.835

4.  Synthesis of lanthanide tag and experimental studies on paramagnetically induced residual dipolar couplings.

Authors:  Ali Yassin; Bilal Nehmeh; Sally El Kantar; Yara Al Kazzaz; Elias Akoury
Journal:  BMC Chem       Date:  2022-07-21
  4 in total

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