| Literature DB >> 27250517 |
Gongming Zhu1, Junxian Yang1, Guangjun Bao1, Ming Zhang1, Jing Li1, Yiping Li1, Wangsheng Sun1, Liang Hong2, Rui Wang3.
Abstract
A catalyst-controlled switch of regioselectivity in asymmetric allylic alkylation of oxazolones with MBHCs was described. The SN2'-SN2' reaction catalysed by a quinine-derived base produced γ-selective secondary allylic oxazolone derivatives, whereas the addition-elimination reaction catalysed by an amino acid-derived bifunctional urea catalyst provided β-selective primary adducts.Entities:
Year: 2016 PMID： 27250517 DOI： 10.1039/c6cc03246j
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222