Literature DB >> 27247842

Is Metabolic Syndrome On the Radar? Improving Real-Time Detection of Metabolic Syndrome and Physician Response by Computerized Scan of the Electronic Medical Record.

Kingwai Lui1, Gagandeep Randhawa1, Vicken Totten2, Adam E Smith3, Joachim Raese1.   

Abstract

OBJECTIVE: Metabolic syndrome is a common underdiagnosed condition among psychiatric patients exacerbated by second-generation antipsychotics, with the exception of aripiprazole and ziprasidone. This study evaluated the prescribing and treating behavior with regard to antipsychotics and metabolic syndrome of psychiatrists before and after implementation of a mandatory admission order set and electronic notification of results.
METHOD: Baseline data from 9,100 consecutive psychiatric admissions to a mental health hospital (July 2013-July 2014) were compared to postintervention data (July 2014-January 2015), which included 1,499 consecutive patient records. The intervention initiated standardized admission testing with electronic notification to psychiatrists when patients met metabolic syndrome criteria (according to Axis III of the DSM-IV). Charts were examined for inclusion of this diagnosis at discharge and for treatment changes.
RESULTS: At baseline, only 2.4% of patients (n = 214) were evaluated for metabolic syndrome. Of these, 34.5% (0.8% of the total sample) met metabolic syndrome criteria. Only 15 patients (0.16%) were comprehensively treated. No chart listed metabolic syndrome under Axis III of the DSM-IV. After the intervention, the diagnosis of patients meeting the criteria for metabolic syndrome increased from 0% to 29.3%. Less than 3% of patients were switched to drugs with a more benign metabolic profile. All patients who continued on second-generation antipsychotics had metabolic retesting. Thirty-eight experienced a significant and rapid increase in triglyceride levels after only 3 to 17 days.
CONCLUSIONS: Mandatory intake testing increases the number of patients evaluated for metabolic syndrome. Electronic alerts increase the inclusion of metabolic syndrome among discharge diagnoses but rarely affect prescribing practices.

Entities:  

Mesh:

Substances:

Year:  2016        PMID: 27247842      PMCID: PMC4874762          DOI: 10.4088/PCC.15m01849

Source DB:  PubMed          Journal:  Prim Care Companion CNS Disord        ISSN: 2155-7780


  55 in total

Review 1.  Why don't physicians follow clinical practice guidelines? A framework for improvement.

Authors:  M D Cabana; C S Rand; N R Powe; A W Wu; M H Wilson; P A Abboud; H R Rubin
Journal:  JAMA       Date:  1999-10-20       Impact factor: 56.272

2.  Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review.

Authors:  D L Hunt; R B Haynes; S E Hanna; K Smith
Journal:  JAMA       Date:  1998-10-21       Impact factor: 56.272

Review 3.  Metabolic monitoring for patients treated with antipsychotic medications.

Authors:  Tony A Cohn; Michael J Sernyak
Journal:  Can J Psychiatry       Date:  2006-07       Impact factor: 4.356

Review 4.  Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies.

Authors:  Floriana S Luppino; Leonore M de Wit; Paul F Bouvy; Theo Stijnen; Pim Cuijpers; Brenda W J H Penninx; Frans G Zitman
Journal:  Arch Gen Psychiatry       Date:  2010-03

5.  Incidence of newly diagnosed diabetes attributable to atypical antipsychotic medications.

Authors:  Douglas L Leslie; Robert A Rosenheck
Journal:  Am J Psychiatry       Date:  2004-09       Impact factor: 18.112

6.  Effects of FDA advisories on the pharmacologic treatment of ADHD, 2004-2008.

Authors:  Rachel Kornfield; Sydeaka Watson; Ashley S Higashi; Rena M Conti; Stacie B Dusetzina; Craig F Garfield; E Ray Dorsey; Haiden A Huskamp; G Caleb Alexander
Journal:  Psychiatr Serv       Date:  2013-04-01       Impact factor: 3.084

7.  A UK audit of screening for the metabolic side effects of antipsychotics in community patients.

Authors:  Thomas R E Barnes; Carol Paton; Mary-Rose Cavanagh; Elizabeth Hancock; David M Taylor
Journal:  Schizophr Bull       Date:  2007-05-04       Impact factor: 9.306

8.  Comparison of metabolic syndrome incidence among schizophrenia patients treated with aripiprazole versus olanzapine or placebo.

Authors:  Gilbert J L'Italien; Daniel E Casey; Hong J Kan; William H Carson; Ronald N Marcus
Journal:  J Clin Psychiatry       Date:  2007-10       Impact factor: 4.384

9.  Quality of medical care and excess mortality in psychiatric patients--a nationwide register-based study in Sweden.

Authors:  Emma Björkenstam; Rickard Ljung; Bo Burström; Ellenor Mittendorfer-Rutz; Johan Hallqvist; Gunilla Ringbäck Weitoft
Journal:  BMJ Open       Date:  2012-02-24       Impact factor: 2.692

Review 10.  Relative risk of diabetes, dyslipidaemia, hypertension and the metabolic syndrome in people with severe mental illnesses: systematic review and metaanalysis.

Authors:  David P J Osborn; Christine A Wright; Gus Levy; Michael B King; Raman Deo; Irwin Nazareth
Journal:  BMC Psychiatry       Date:  2008-09-25       Impact factor: 3.630

View more
  1 in total

1.  Systematic Quality Improvement and Metabolic Monitoring for Individuals Taking Antipsychotic Drugs.

Authors:  Takahiro Soda; Jennifer Richards; Bradley N Gaynes; Michelle Cueva; Jeffrey Laux; Christine McClain; Rachel Frische; Lisa K Lindquist; Gary S Cuddeback; L Fredrik Jarskog
Journal:  Psychiatr Serv       Date:  2021-04-23       Impact factor: 4.157

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.