Literature DB >> 27246488

Magnetic resonance imaging assessment of degenerative cervical myelopathy: a review of structural changes and measurement techniques.

Aria Nouri1,2, Allan R Martin1,2, David Mikulis3,2, Michael G Fehlings1,2.   

Abstract

Degenerative cervical myelopathy encompasses a spectrum of age-related structural changes of the cervical spine that result in static and dynamic injury to the spinal cord and collectively represent the most common cause of myelopathy in adults. Although cervical myelopathy is determined clinically, the diagnosis requires confirmation via imaging, and MRI is the preferred modality. Because of the heterogeneity of the condition and evolution of MRI technology, multiple techniques have been developed over the years in an attempt to quantify the degree of baseline severity and potential for neurological recovery. In this review, these techniques are categorized anatomically into those that focus on bone, ligaments, discs, and the spinal cord. In addition, measurements for the cervical spine canal size and sagittal alignment are also described briefly. These tools have resulted collectively in the identification of numerous useful parameters. However, the development of multiple techniques for assessing the same feature, such as cord compression, has also resulted in a number of challenges, including introducing ambiguity in terms of which methods to use and hindering effective comparisons of analysis in the literature. In addition, newer techniques that use advanced MRI are emerging and providing exciting new tools for assessing the spinal cord in patients with degenerative cervical myelopathy.

Entities:  

Keywords:  CR = compression ratio; CSA = cross-sectional area; DCM = degenerative cervical myelopathy; DTI = diffusion tensor imaging; FA = fractional anisotropy; IVD = intervertebral disc; JOA = Japanese Orthopaedic Association; LF = ligamentum flavum; MCC = maximum canal compromise; MRS = MR spectroscopy; MSCC = maximum spinal cord compression; MT = magnetization transfer; MTR = MT ratio; MWF = myelin water fraction; NAA = N-acetyl aspartate; OPLL = ossification of the posterior longitudinal ligament; PLL = posterior longitudinal ligament; ROI = region of interest; T1WI = T1-weighted imaging; T2WI = T2-weighted imaging; VB = vertebral body; cervical spondylotic myelopathy; compressive myelopathy; diffusion tensor imaging; disc disease; fMRI = functional MRI; mJOA = modified JOA; method; spine; stenosis

Mesh:

Year:  2016        PMID: 27246488     DOI: 10.3171/2016.3.FOCUS1667

Source DB:  PubMed          Journal:  Neurosurg Focus        ISSN: 1092-0684            Impact factor:   4.047


  41 in total

Review 1.  [Spondylotic cervical myelopathy : Indication of surgical treatment].

Authors:  W Pepke; H Almansour; M Richter; M Akbar
Journal:  Orthopade       Date:  2018-06       Impact factor: 1.087

2.  A Novel MRI Biomarker of Spinal Cord White Matter Injury: T2*-Weighted White Matter to Gray Matter Signal Intensity Ratio.

Authors:  A R Martin; B De Leener; J Cohen-Adad; D W Cadotte; S Kalsi-Ryan; S F Lange; L Tetreault; A Nouri; A Crawley; D J Mikulis; H Ginsberg; M G Fehlings
Journal:  AJNR Am J Neuroradiol       Date:  2017-04-20       Impact factor: 3.825

3.  Cervical compressive myelopathy: flow analysis of cerebrospinal fluid using phase-contrast magnetic resonance imaging.

Authors:  Yun Jung Bae; Joon Woo Lee; Eugene Lee; Jin S Yeom; Ki-Jeong Kim; Heung Sik Kang
Journal:  Eur Spine J       Date:  2016-11-17       Impact factor: 3.134

4.  Assessment of degenerative cervical stenosis on T2-weighted MR imaging: sensitivity to change and reliability of mid-sagittal and axial plane metrics.

Authors:  Keerthana Sritharan; Uphar Chamoli; Jeffrey Kuan; Ashish D Diwan
Journal:  Spinal Cord       Date:  2019-09-26       Impact factor: 2.772

5.  Laminectomy alone versus laminectomy with fusion for degenerative cervical myelopathy: a long-term study of a national cohort.

Authors:  Eddie de Dios; Robert F Heary; Lars Lindhagen; Anna MacDowall
Journal:  Eur Spine J       Date:  2021-12-01       Impact factor: 2.721

6.  Considerations for Mean Upper Cervical Cord Area Implementation in a Longitudinal MRI Setting: Methods, Interrater Reliability, and MRI Quality Control.

Authors:  C Chien; V Juenger; M Scheel; A U Brandt; F Paul
Journal:  AJNR Am J Neuroradiol       Date:  2020-01-23       Impact factor: 3.825

7.  T1 Mapping for Microstructural Assessment of the Cervical Spinal Cord in the Evaluation of Patients with Degenerative Cervical Myelopathy.

Authors:  G Baucher; H Rasoanandrianina; S Levy; L Pini; L Troude; P-H Roche; V Callot
Journal:  AJNR Am J Neuroradiol       Date:  2021-05-13       Impact factor: 4.966

8.  Compensatory brainstem functional and structural connectivity in patients with degenerative cervical myelopathy by probabilistic tractography and functional MRI.

Authors:  Chencai Wang; Azim Laiwalla; Noriko Salamon; Benjamin M Ellingson; Langston T Holly
Journal:  Brain Res       Date:  2020-09-17       Impact factor: 3.252

9.  Tract-Specific Volume Loss on 3T MRI in Patients With Cervical Spondylotic Myelopathy.

Authors:  Benjamin S Hopkins; Kenneth A Weber; Michael Brendan Cloney; Monica Paliwal; Todd B Parrish; Zachary A Smith
Journal:  Spine (Phila Pa 1976)       Date:  2018-10-15       Impact factor: 3.241

10.  Thoracic full-endoscopic unilateral laminotomy with bilateral decompression for treating ossification of the ligamentum flavum with myelopathy.

Authors:  Yong-Peng Lin; Rui Lin; Song Chen; Si-Yuan Rao; Shuai Zhao; Tao Wen; Hong-Shen Wang; Wei-Xiong Hu; Bing-Xin Liu; Xin-Yi Li; Yong-Jin Li; Bo-Lai Chen
Journal:  Ann Transl Med       Date:  2021-06
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