Amerigo Rossi1, Carol Ewing Garber2, Monica Ortiz3, Viswanathan Shankar4, Gary L Goldberg5, Nicole S Nevadunsky6. 1. Division of Athletic Training, Health and Exercise Science, Long Island University Brooklyn, 1 University Plaza, HS 311a, Brooklyn, NY 11238, USA; Department of Biobehavioral Sciences, Teachers College Columbia University, 525 West 120(th) Street, Box 93, New York, NY 10027, USA. Electronic address: amerigo.rossi@liu.edu. 2. Department of Biobehavioral Sciences, Teachers College Columbia University, 525 West 120(th) Street, Box 93, New York, NY 10027, USA. Electronic address: garber@tc.columbia.edu. 3. Department of Health & Nutrition Sciences, Brooklyn College, 2900 Bedford Avenue, Brooklyn, NY 11210, USA. Electronic address: mrossi@health.nyc.gov. 4. Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue Bronx, NY 10461, USA. Electronic address: shankar.viswanathan@einstein.yu.edu. 5. Department of Obstetrics & Gynecology and Women's Health, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue Bronx, NY 10461, USA. Electronic address: ggoldber@mentefiore.org. 6. Department of Obstetrics & Gynecology and Women's Health, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA; Albert Einstein Cancer Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue Bronx, NY 10461, USA. Electronic address: nnevadun@montefiore.org.
Abstract
PURPOSE: Determine the feasibility of a 12-week physical activity intervention for obese, socioculturally diverse endometrial cancer survivors and to evaluate whether the intervention improves physical activity behavior, physical function, waist circumference, and quality of life. METHODS:Obese endometrial cancer survivors from Bronx, NY were assigned to either a 12-week physical activity intervention of behavioral counseling, physical activity and home-based walking (n=25), or wait-list control group (n=15). Mixed-design ANOVA (2 groups×2 time points) were analyzed to determine differences between the intervention and the control for the Yale Physical Activity Survey, six-minute walk test, 30-second chair stand test, waist circumference, and Functional Assessment of Cancer Therapy-Endometrial questionnaire. Data are presented as mean±standard deviation. RESULTS: The sample was diverse (38% non-Hispanic black, 38% Hispanic, 19% non-Hispanic white). Mean Body Mass Index was 37.3±6.5kg·m(-2). Although recruitment rate was low (20% of 140 contacted), 15 of 25 participants in the intervention group attended 75-100% of scheduled sessions. Participants reported walking 118±79min/week at home. There were large effect sizes for the improvements in the six-minute walk test (22±17m vs. 1±22m, d=1.10), waist circumference (-5.3±5.3cm vs. 2.6±6.7cm, d=-1.32), quality of life (10±12 vs. -1±11, d=0.86) and walking self-efficacy (24±30% vs. 1±55%, d=0.87) compared to the control group. CONCLUSIONS: The intervention appeared feasible in this population. The results show promising effects on several outcomes that should be confirmed in a larger randomized control trial, with more robust recruitment strategies.
RCT Entities:
PURPOSE: Determine the feasibility of a 12-week physical activity intervention for obese, socioculturally diverse endometrial cancer survivors and to evaluate whether the intervention improves physical activity behavior, physical function, waist circumference, and quality of life. METHODS:Obese endometrial cancer survivors from Bronx, NY were assigned to either a 12-week physical activity intervention of behavioral counseling, physical activity and home-based walking (n=25), or wait-list control group (n=15). Mixed-design ANOVA (2 groups×2 time points) were analyzed to determine differences between the intervention and the control for the Yale Physical Activity Survey, six-minute walk test, 30-second chair stand test, waist circumference, and Functional Assessment of Cancer Therapy-Endometrial questionnaire. Data are presented as mean±standard deviation. RESULTS: The sample was diverse (38% non-Hispanic black, 38% Hispanic, 19% non-Hispanic white). Mean Body Mass Index was 37.3±6.5kg·m(-2). Although recruitment rate was low (20% of 140 contacted), 15 of 25 participants in the intervention group attended 75-100% of scheduled sessions. Participants reported walking 118±79min/week at home. There were large effect sizes for the improvements in the six-minute walk test (22±17m vs. 1±22m, d=1.10), waist circumference (-5.3±5.3cm vs. 2.6±6.7cm, d=-1.32), quality of life (10±12 vs. -1±11, d=0.86) and walking self-efficacy (24±30% vs. 1±55%, d=0.87) compared to the control group. CONCLUSIONS: The intervention appeared feasible in this population. The results show promising effects on several outcomes that should be confirmed in a larger randomized control trial, with more robust recruitment strategies.
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