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Literature DB >> 27246034

Purification and Adoptive Transfer of Group 3 Gut Innate Lymphoid Cells.

Xiaohuan Guo¹, Kevin Muite², Joanna Wroblewska², Yang-Xin Fu².

Abstract

Recent studies have identified several related but distinct innate lymphoid cells (ILCs) populations that are relatively enriched in the intestinal mucosal and protect the host from various infections. Among ILCs, group 3 ILCs (ILC3s) produce lymphotoxin and IL-22, and play important roles in the development of the immune system and host-bacteria interactions. Here, we describe methods for the isolation and purification of ILC3s from the mouse intestine, and the adoptive transfer of purified ILC3s into recipient mice.

Entities: Disease Gene Species

Keywords: Adoptive transfer; Group 3 Innate lymphoid cells; Intestine; Purification; Rag1

Mesh：

Substances：

Year: 2016 PMID： 27246034 DOI： 10.1007/978-1-4939-3603-8_18

Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745

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Cited

6 in total

1. LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection.

Authors: Goo-Young Seo; Jr-Wen Shui; Daisuke Takahashi; Christina Song; Qingyang Wang; Kenneth Kim; Zbigniew Mikulski; Shilpi Chandra; Daniel A Giles; Sonja Zahner; Pyeung-Hyeun Kim; Hilde Cheroutre; Marco Colonna; Mitchell Kronenberg
Journal: Cell Host Microbe Date: 2018-08-08 Impact factor: 21.023

2. Innate Lymphoid Cells Are Required for Endometrial Resistance to Chlamydia trachomatis Infection.

Authors: Hong Xu; Xin Su; Yujie Zhao; Lingli Tang; Jianlin Chen; Guangming Zhong
Journal: Infect Immun Date: 2020-06-22 Impact factor: 3.441

3. Adoptive Transfer of Group 3-Like Innate Lymphoid Cells Restores Mouse Colon Resistance to Colonization of a Gamma Interferon-Susceptible Chlamydia muridarum Mutant.

Authors: Ying He; Hong Xu; Chenchen Song; John J Koprivsek; Bernard Arulanandam; Huixiang Yang; Lijian Tao; Guangming Zhong
Journal: Infect Immun Date: 2021-01-19 Impact factor: 3.441

Purification and Adoptive Transfer of Group 3 Gut Innate Lymphoid Cells.

1. LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection.

2. Innate Lymphoid Cells Are Required for Endometrial Resistance to Chlamydia trachomatis Infection.

3. Adoptive Transfer of Group 3-Like Innate Lymphoid Cells Restores Mouse Colon Resistance to Colonization of a Gamma Interferon-Susceptible Chlamydia muridarum Mutant.

4. In Vivo Photolabeling of Cells in the Colon to Assess Migratory Potential of Hematopoietic Cells in Neonatal Mice.

5. Bacterial Infection Allows for Functional Examination of Adoptively Transferred Mouse Innate Lymphoid Cell Subsets.

6. A mouse model of Citrobacter rodentium oral infection and evaluation of innate and adaptive immune responses.