Marcelo P Pereira1, Lilian T B Gobbi2, Quincy J Almeida3. 1. Posture and Locomotion Studies Laboratory, UNESP - Univ Estadual Paulista, Physical Education Departament, Bioscience Institute, Rio Claro, SP, Brazil; Research Group for Neuromotor Rehabilitation, Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; Sun Life Financial Movement Disorders Research and Rehabilitation Centre, Wilfrid Laurier University, Waterloo, ON, Canada. 2. Posture and Locomotion Studies Laboratory, UNESP - Univ Estadual Paulista, Physical Education Departament, Bioscience Institute, Rio Claro, SP, Brazil. 3. Sun Life Financial Movement Disorders Research and Rehabilitation Centre, Wilfrid Laurier University, Waterloo, ON, Canada. Electronic address: qalmeida@wlu.ca.
Abstract
INTRODUCTION: The role of proprioceptive integration impairments as the potential mechanism underlying Freezing of gait (FOG) in Parkinson's disease (PD) is still an open debate. The effects of muscle vibration (a well-known manipulation of proprioception) could provide the answer to the debate. The aim of this study was to determine whether proprioceptive manipulation, through muscle vibration, could reduce FOG severity. METHODS: Sixteen PD patients who experience FOG were required to walk with small step lengths (15 cm). Cylindrical vibration devices were positioned on triceps surae tendon. Three vibration conditions were tested: No vibration (OFF), vibration on the less affected limb (LA), or on the more affected limb (MA). Additionally, we assessed the effects of applying vibration before and after FOG onset. The FOG duration and the foot used to take the next step were assessed. RESULTS: FOG significantly decreased only with vibration of LA in comparison to OFF, and when vibration was applied after FOG onset. CONCLUSION: Our results show that muscle vibration is a promising technique to alleviate the severity of FOG. Improvements to FOG behavior were restricted to the less affected limb, suggesting that only the less damaged side of the basal ganglia may have preserved capacity to process sensory feedback. These results also suggest the likelihood of sensory deficits in FOG that cannot be explained by cognitive mechanisms, since vibration effects were only observed unilaterally.
INTRODUCTION: The role of proprioceptive integration impairments as the potential mechanism underlying Freezing of gait (FOG) in Parkinson's disease (PD) is still an open debate. The effects of muscle vibration (a well-known manipulation of proprioception) could provide the answer to the debate. The aim of this study was to determine whether proprioceptive manipulation, through muscle vibration, could reduce FOG severity. METHODS: Sixteen PDpatients who experience FOG were required to walk with small step lengths (15 cm). Cylindrical vibration devices were positioned on triceps surae tendon. Three vibration conditions were tested: No vibration (OFF), vibration on the less affected limb (LA), or on the more affected limb (MA). Additionally, we assessed the effects of applying vibration before and after FOG onset. The FOG duration and the foot used to take the next step were assessed. RESULTS:FOG significantly decreased only with vibration of LA in comparison to OFF, and when vibration was applied after FOG onset. CONCLUSION: Our results show that muscle vibration is a promising technique to alleviate the severity of FOG. Improvements to FOG behavior were restricted to the less affected limb, suggesting that only the less damaged side of the basal ganglia may have preserved capacity to process sensory feedback. These results also suggest the likelihood of sensory deficits in FOG that cannot be explained by cognitive mechanisms, since vibration effects were only observed unilaterally.
Authors: Paulo H S Pelicioni; Jasmine C Menant; Mark D Latt; Stephen R Lord Journal: Int J Environ Res Public Health Date: 2019-06-23 Impact factor: 3.390
Authors: Erich Talamoni Fonoff; Andrea C de Lima-Pardini; Daniel Boari Coelho; Bernardo Assumpção Monaco; Birajara Machado; Carolina Pinto de Souza; Maria Gabriela Dos Santos Ghilardi; Clement Hamani Journal: Front Neurol Date: 2019-08-27 Impact factor: 4.003