Literature DB >> 27245678

Snake venom toxins: toxicity and medicinal applications.

Yau Sang Chan1, Randy Chi Fai Cheung2, Lixin Xia3, Jack Ho Wong4, Tzi Bun Ng5, Wai Yee Chan6.   

Abstract

Snake venoms are complex mixtures of small molecules and peptides/proteins, and most of them display certain kinds of bioactivities. They include neurotoxic, cytotoxic, cardiotoxic, myotoxic, and many different enzymatic activities. Snake envenomation is a significant health issue as millions of snakebites are reported annually. A large number of people are injured and die due to snake venom poisoning. However, several fatal snake venom toxins have found potential uses as diagnostic tools, therapeutic agent, or drug leads. In this review, different non-enzymatically active snake venom toxins which have potential therapeutic properties such as antitumor, antimicrobial, anticoagulating, and analgesic activities will be discussed.

Entities:  

Keywords:  Snake; Therapeutic; Toxin; Venom

Mesh:

Substances:

Year:  2016        PMID: 27245678     DOI: 10.1007/s00253-016-7610-9

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  23 in total

Review 1.  Biotoxins in muscle regeneration research.

Authors:  Mohamed A A Mahdy
Journal:  J Muscle Res Cell Motil       Date:  2019-07-29       Impact factor: 2.698

2.  Variation in the Protein Composition and Biological Activity of King Cobra (Ophiophagus hannah) Venoms.

Authors:  Pakamas Wongtay; Papassara Sangtanoo; Polkit Sangvanich; Aphichart Karnchanatat
Journal:  Protein J       Date:  2019-10       Impact factor: 2.371

3.  Crotalus atrox disintegrin reduces hemorrhagic transformation by attenuating matrix metalloproteinase-9 activity after middle cerebral artery occlusion in hyperglycemic male rats.

Authors:  Devin W McBride; Eric C K Gren; Wayne Kelln; William K Hayes; John H Zhang
Journal:  J Neurosci Res       Date:  2018-09-22       Impact factor: 4.164

Review 4.  Computational Studies of Snake Venom Toxins.

Authors:  Paola G Ojeda; David Ramírez; Jans Alzate-Morales; Julio Caballero; Quentin Kaas; Wendy González
Journal:  Toxins (Basel)       Date:  2017-12-22       Impact factor: 4.546

Review 5.  Antimicrobials from Venomous Animals: An Overview.

Authors:  Tania Yacoub; Mohamad Rima; Marc Karam; Jean-Marc Sabatier And Ziad Fajloun
Journal:  Molecules       Date:  2020-05-21       Impact factor: 4.411

6.  A Case Series of Snake Venom Pharmacopuncture for Chemotherapy-Induced Peripheral Neuropathy: A Retrospective Observational Study.

Authors:  Si Yeon Song; Kyeore Bae; Kwhang Ho Shin; Hwa-Seung Yoo
Journal:  J Pharmacopuncture       Date:  2017-11-13

Review 7.  Snake Venoms in Cancer Therapy: Past, Present and Future.

Authors:  Li Li; Jianzhong Huang; Yao Lin
Journal:  Toxins (Basel)       Date:  2018-08-29       Impact factor: 4.546

Review 8.  Immunological Responses to Envenomation.

Authors:  Rachael Y M Ryan; Jamie Seymour; Alex Loukas; J Alejandro Lopez; Maria P Ikonomopoulou; John J Miles
Journal:  Front Immunol       Date:  2021-05-10       Impact factor: 7.561

9.  Assigning biological function using hidden signatures in cystine-stabilized peptide sequences.

Authors:  S M Ashiqul Islam; Christopher Michel Kearney; Erich J Baker
Journal:  Sci Rep       Date:  2018-06-13       Impact factor: 4.379

10.  Cell migration inhibition activity of a non-RGD disintegrin from Crotalus durissus collilineatus venom.

Authors:  Isadora Sousa de Oliveira; Rafaella Varzoni Manzini; Isabela Gobbo Ferreira; Iara Aimê Cardoso; Karla de Castro Figueiredo Bordon; Ana Rita Thomazela Machado; Lusânia Maria Greggi Antunes; José Cesar Rosa; Eliane Candiani Arantes
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2018-10-20
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