| Literature DB >> 27244962 |
Natthakul Bunnueang, Sutthiporn Kongpheng, Patcharin Yadrak, Pattamarat Rattanachuay, Saowapar Khianngam, Pharanai Sukhumungoon.
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen causing nosocomial and other types of infections worldwide. In a one-year survey of patients in two tertiary hospitals, namely, Maharaj Nakhon Si Thammarat and VachiraPhuket Hospitals, southern Thailand, 64 MRSA strains (prevalence of 8.1%) were obtained mainly from the elderly (> 45 years of age). PCR-based assay revealed high prevalence of virulence genes, femB (30%) and spa (34%), and of SCCmec type II from VachiraPhuket (36%) and Maharaj Nakhon Si Thammarat (38%) Hospitals. The majority of MRSA strains were resistant to clindamycin (98%), erythromycin (95%), gentamicin (84%), and tetracycline (80%), while still sensitive to chloramphenicol, cotrimoxazole, fusidic acid, and vancomycin. These data are important for effective treatment of MRSA-infected patients and for implementing control strategies to prevent spread of MRSA within hospitals.Entities:
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Year: 2016 PMID： 27244962
Source DB: PubMed Journal: Southeast Asian J Trop Med Public Health ISSN： 0125-1562 Impact factor: 0.267