BACKGROUND: Postcoital genital washing by uncircumcised men may affect the risk of male HIV acquisition. METHOD: We assessed the association between self-reported washing after sex in 2976 initially HIV-negative, uncircumcised men enrolled in a prospective cohort study in Rakai, Uganda. RESULTS: Data from the 2976 participants who reported sexual intercourse in the past 12 months contributed 4290 visits, with 7316.6 person-years of observation during the 2-year follow-up. The overall HIV-incidence was 1.28/100 person-years 95%CI (1.04-1.57). About 91.0% of men reported washing their penis after sex, and their HIV incidence was 1.34/100 person-years (95%CI 1.08-1.66), compared with an incidence of 0.62/100 person-years (95%CI 0.17-1.60) in men who did not wash their penis after intercourse. Using Poisson multivariable regression, the adjusted incidence rate ratio of HIV acquisition associated with postcoital washing was 1.94 (95%CI 0.71-5.29). CONCLUSION: Postcoital penile washing, as practiced in this rural African population does not afford protection from HIV acquisition among uncircumcised men, and may increase risk.
BACKGROUND: Postcoital genital washing by uncircumcised men may affect the risk of male HIV acquisition. METHOD: We assessed the association between self-reported washing after sex in 2976 initially HIV-negative, uncircumcised men enrolled in a prospective cohort study in Rakai, Uganda. RESULTS: Data from the 2976 participants who reported sexual intercourse in the past 12 months contributed 4290 visits, with 7316.6 person-years of observation during the 2-year follow-up. The overall HIV-incidence was 1.28/100 person-years 95%CI (1.04-1.57). About 91.0% of men reported washing their penis after sex, and their HIV incidence was 1.34/100 person-years (95%CI 1.08-1.66), compared with an incidence of 0.62/100 person-years (95%CI 0.17-1.60) in men who did not wash their penis after intercourse. Using Poisson multivariable regression, the adjusted incidence rate ratio of HIV acquisition associated with postcoital washing was 1.94 (95%CI 0.71-5.29). CONCLUSION:Postcoital penile washing, as practiced in this rural African population does not afford protection from HIV acquisition among uncircumcised men, and may increase risk.
Authors: Rupert Kaul; Cindy M Liu; Daniel E Park; Ronald M Galiwango; Aaron A R Tobian; Jessica L Prodger Journal: Viruses Date: 2022-05-27 Impact factor: 5.818
Authors: Jessica L Prodger; Alison G Abraham; Aaron Ar Tobian; Daniel E Park; Maliha Aziz; Kelsey Roach; Ronald H Gray; Lane Buchanan; Godfrey Kigozi; Ronald M Galiwango; Joseph Ssekasanvu; James Nnamutete; Joseph Kagaayi; Rupert Kaul; Cindy M Liu Journal: JCI Insight Date: 2021-04-22
Authors: Cindy M Liu; Jessica L Prodger; Aaron A R Tobian; Alison G Abraham; Godfrey Kigozi; Bruce A Hungate; Maliha Aziz; Fred Nalugoda; Sanjeev Sariya; David Serwadda; Rupert Kaul; Ronald H Gray; Lance B Price Journal: MBio Date: 2017-07-25 Impact factor: 7.867